Les neuropathies liées au VIH/SIDA: une étude clinique chez les patients infectés par le VIH au Centre d’Excellence VIH/SIDA de l’Université de Lubumbashi

Kabongo, Joe; Kaputu-Kalala-Malu, Célestin; Luboya, Oscar Numbi; Mutombo, Valerien; Ntambwe, Abel; Mapatano, Mala Ali; Mukendi, Kavulu Mayamba

doi:10.11604/pamj.2015.20.392.5799

Cited by 1 publication

(1 citation statement)

References 11 publications

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“…In 2011, the prevalence of NeuP using the DN4 questionnaire in 600 patients with HIV was 20% [ 54 , 55 ]. In the Democratic Republic of Congo, 3.12% of the patients with HIV had neurological complications, and over 80% had NeuP [ 56 ]. NeuP can occur at any stage of the HIV/AIDS progression and it affects 55% of the patients taking ARV drugs for various reasons (the virus itself, HIV-related infections, ARV, and anti-TB drugs) [ 51 , 52 ].…”

Section: Discussionmentioning

confidence: 99%

Neuropathic pain in Mali: The current situation, comprehensive hypothesis, which therapeutic strategy for Africa?

Maiga¹,

Sangho

Konipo

et al. 2021

eNeurologicalSci

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Introduction According to the taxonomy of the International Association for the Study of Pain (IASP 2011), neuropathic pain (NeuP) is defined as “ pain caused by a lesion or disease of the somatosensory nervous system ”. NeuP is currently well-defined clinically, despite a high degree of etiological variation, and it has become a significant public health problem. This work aimed to study the situation regarding NeuP in current practice in Mali, as well as to analyze the therapeutic environment of the patients. Methodology This was a retrospective and cross-sectional study, carried out in two phases: (1) compilation of the files of patients according to the ICD-11, over a period of 24 months (2) a second prospective phase regarding the Knowledge, Attitudes, and Practices (KAP) of general practitioners and neurologists in regard to NeuP. The focus of the first phase of the study was the files of the patients who had undergone a consultation at the Gabriel Touré UHC. The second phase of the study focused on the general practitioners (Community Health Centers (comHC) of Bamako) and neurologists (Malian or not). Results Over the period of the study, 7840 patients were seen in consultation in the Department of Neurology, of whom 903 for NeuP, thus amounting to a NeuP frequency of 11.5%. Women accounted for 58.9% (532/903), with a sex ratio of 1.4. Using a comparative normal law, the difference in frequency was statistically significant between males and females ( p < 10 −7 ) and between two age groups (p 〈10 −3 ). The 49–58 years of age group was represented the most. Diabetic NeuP (21%), lumbar radiculopathies (14%), HIV/AIDS NeuP (13%), and post-stroke NeuP (11%) were the most represented. The survey among the carers revealed: a need for training, a low level of compliance with the therapeutic guidelines, and the use of traditional medicine by the patients. Discussion/conclusion This work confirms that NeuP is encountered frequently in current practice, and its optimal management will involve specific training of carers and improvement of access to the medications recommended in this indication. In light of this issue, we revisit the debate regarding the concept of essential medications and the relevance of taking into account effective medications for the treatment of NeuP.

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Section: Discussionmentioning

confidence: 99%