Les lymphomes malins non hodgkiniens conjonctivo-orbitaires

Benabid, L; Desablens, B; Brevet, Marie; Malthieu, D; Milazzo, S.; Turut, P

doi:10.1016/s0181-5512(05)81138-6

Cited by 5 publications

(3 citation statements)

References 17 publications

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“…Non-Hodgkin's lymphoma (NHL) accounts for 35% of all hematological malignancies. Mantle cell lymphoma (LCM) is a newly described entity [2][3][4]. Indeed, in the early 1990s, two authors described and characterized cytologically, then cytogenetically, a particular form of NHL whose tumor cell derives from the area of the mantle that will be at the origin of the term "mantle cell lymphoma" [5][6][7] This represents 6% of non-Hodgkin lymphoma cases.…”

Section: Discussionmentioning

confidence: 99%

Bilateral Exophtalmy, Revealing a Lymphoma not Hodgkinien of the Coat Type

Mouzari¹,

Hamed²,

Zerrouk³

et al. 2018

Ophthalmol Res

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Introduction: The Non hodgkinien lymphma (NHL) orbital location is a rare tumor, difficult to diagnose. The mantle cell lymphoma represents 6% of cases of LNH B. We report a patient of 60 years with bilateral exophthalmia revealing a mantle cell lymphoma. Clinical Observation: A man of 60 years ran for ophthalmological emergencies in an array of orbital cellulitis of the right eye. This swelling was that day, painful, inflammatory, axile, irreducible, and non-pulsatile, with limited horizontal movement of the eyeball. In general terms, the patient has axillary lymph nodes and supraclavicular without splenomegaly. A biopsy of the orbital mass produced by trans-conjunctival, concluded in a non-Hodgkin lymphoma B type mantle (CD20 +, CD5 +, cyclin D1 +). The assessment of extension realized in the Hematology Clinic department shows that this is a mantle cell lymphoma NHL B stage (nodes above and below the diaphragm, bilateral eyelid damage, spinal cord and location). After 3 treatments Rituximab-CHOP and DHAP-Rituximab treatments 3, obtaining a complete remission. Discussion: The mantle cell lymphoma represents about 6% of NHL. Its incidence is estimated between 0.07 and three cases per 100 000 population per year. The geographical area and ethnicity shows a higher frequency in Caucasians than in African Americans. Ocular involvement in the NHL is a rare event, as evidenced by the limited number of cases reported in the literature. It may be opening that is the case of our patient, or alter the course of lymphoma known. Conclusion: The eye location of mantle cell lymphoma is a rare entity. The clinical picture of this location can be misleading, particularly that of orbital cellulitis. The tumor biopsy confirms the diagnosis. Despite the treatment regimens, the prognosis of this type of lymphoma is reserved.

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Section: Discussionmentioning

confidence: 99%

Bilateral Exophtalmy, Revealing a Lymphoma not Hodgkinien of the Coat Type

Mouzari¹,

Hamed²,

Zerrouk³

et al. 2018

Ophthalmol Res

View full text Add to dashboard Cite

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“…Non-Hodgkin's lymphoma with orbital location accounts for 5 to 10% of orbital expansive processes [1][2][3]. According to Ducrey [4], they constitute 4% of non-traumatic orbital conditions.…”

Section: Discussionmentioning

confidence: 99%

“…The most common clinical sign is a periocular mass that can lead to exophthalmia or diplopia. The imaging highlights two evocative aspects, a well-defined mass with fuzzy contours that can mold on the eyeball, optic nerve or bone wall, or an infiltrating form extending into the eyelid, the subcutaneous planes or intra and extra-conical adipose tissue and more or less including muscle and optic nerve [2].…”

Section: Discussionmentioning

confidence: 99%