Les changements de vitesse du flux sanguin cérébral, déclenchés par la stimulation chirurgicale, dépendent du niveau de PaCO2

Nitrous oxide added to propofol does not influence the increase in cerebral blood flow velocity elicited by surgical stimulation

“…1,2 Our previous study demonstrated in patients anesthetized with 1.7% sevoflurane plus 60% nitrous oxide (N 2 O) that the increase in CBF velocity elicited by surgical stimulation was attenuated by prior constriction of cerebral vessels through hypocapnia and was augmented by dilation of them through hypercapnia. 3 We currently investigated whether the addition of N 2 O, a potent cerebral vasodilator, to propofol, a cerebral vasoconstrictor, augments the response of CBF velocity to surgical stimulation using transcranial Doppler ultrasonography.…”