Leptospirosis with acute renal failure and paraparesis

Ramakrishna, Pinjala; Naresh, V.; Chakrapani, B; Vengamma, B; Kumar, V Siva

doi:10.4103/0971-4065.43695

Cited by 5 publications

(2 citation statements)

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“…In reviewing the cause of the paraparesis (leptospirosis vs. hyperkalemia), it may be logical to conclude that the paraparesis was secondary to the leptospirosis because of the slow improvement in motor function of both lower limbs despite the early correction of hyperkalemia by hemodialysis. Similar findings were reported by Ramakrishna et al .,[ 1 ] Mumford et al . [ 5 ] and Kitazawa et al .…”

Section: Discussionmentioning

confidence: 99%

“…Leptospirosis is a worldwide disease with predominance in tropical, rural areas and its presentation in combination with paraparesis and Weil's syndrome is uncommon. [ 1 2 ] A thorough knowledge of clinical manifestations is especially valuable in communities that lack diagnostic facilities and hence the need for clinical judgment and suspicion is paramount. [ 3 4 ]…”

Section: Introductionmentioning

confidence: 99%

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An unusual case of Weil′s syndrome with paraparesis

Patil¹,

Patil²,

Sakaria³

et al. 2011

Indian Journal of Critical Care Medicine

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Leptospirosis is an important emerging zoonosis with a worldwide distribution that is characterized by a broad spectrum of clinical manifestations ranging from inapparent infection to fulminant disease. Leptospirosis has protean clinical manifestations. The classical presentation of the disease is an acute biphasic febrile illness with or without jaundice. Unusual clinical manifestations may result from involvement of pulmonary, cardiovascular, neural, gastrointestinal, ocular and other systems. Immunological phenomena secondary to antigenic mimicry may also be an important component of many clinical features and may be responsible for reactive arthritis. The presentation of paraparesis in combination with Weil's syndrome is rare. Few cases were reported with leptospirosis and paraparesis in India and abroad. It is important to bear in mind that leptospiral illness may be a significant component in cases of dual infections or in simultaneous infections with more than two pathogens. Here we are reporting a case of Weil's syndrome with paraparesis in 28-year-old male patient who was critically ill due to severe hepatorenal dysfunction and hyperkalemia.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

An unusual case of Weil′s syndrome with paraparesis

Patil¹,

Patil²,

Sakaria³

et al. 2011

Indian Journal of Critical Care Medicine

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Leptospirosis with transient paraparesis and thrombocytopenia: A case report

Wang

Huang

et al. 2012

Journal of Microbiology, Immunology and Infection

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Leptospirosis is the most widespread zoonosis in the world. We present an unusual case of leptospirosis in a 44-year-old man with severe thrombocytopenia and transient paraparesis. The diagnosis of leptospirosis was confirmed by blood nested polymerase chain reaction, seroconversion of Leptospira IgM and the microscopic agglutination test. Nerve conduction studies were suggestive of early polyneuropathy involving the right peroneal nerve and bilateral sural nerves. Peripheral nerve palsy is a potential clinical feature of leptospirosis.

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Leptospirosis presenting as ascending progressive leg weakness and complicating with acute pancreatitis

Silva

Burg

Locatelli

et al. 2011

The Brazilian Journal of Infectious Diseases

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Leptospirosis is a spirochetal bacterial infection of great public health importance. It has a broad spectrum of clinical manifestations which goes from subclinical infection and self-limited anicteric febrile illness (80-90% of all cases) to icteric leptospiropirosis known as Weil's disease. This is a severe disease characterized by hemorrhage, acute renal failure and jaundice. It is uncommon for leptospirosis to present itself as a primary neurological disease. Additionally, acute pancreatitis is an unusual gastrointestinal manifestation. We report a case of leptospirosis presenting as ascending progressive leg weakness and complicating with acute pancreatitis in an adult patient treated at Hospital Universitário, Universidade Federal de Santa Catarina. The diagnosis was confirmed through ELISA-IgM antibody testing positive for leptospirosis. After antibiotic therapy and support treatment for a few weeks, total resolution of severe manifestations was achieved. Rare and unusual presentations of leptospirosis should be kept in mind in relevant epidemiological scenario.

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Leptospirosis with acute renal failure and paraparesis

Abstract: Leptospirosis is an important zoonosis with a worldwide distribution that is characterized by a broad spectrum of clinical manifestations ranging from inapparent infection to fulminant disease. The presentation of paraparesis in combination with acute renal failure is rare.

Cited by 5 publications

References 1 publication

An unusual case of Weil′s syndrome with paraparesis

An unusual case of Weil′s syndrome with paraparesis

Leptospirosis with transient paraparesis and thrombocytopenia: A case report

Leptospirosis presenting as ascending progressive leg weakness and complicating with acute pancreatitis

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