2000
DOI: 10.1016/s0891-5520(05)70216-6
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Leptospirosis in Latin America

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Cited by 78 publications
(87 citation statements)
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References 49 publications
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“…These are the most common findings reported in leptospirosis. 1,7,8,9,17,19 Hemorrhagic manifestations are characteristic of Weil disease, and are potentially fatal. Patients can develop important hemodynamic abnormalities, secondary to hypovolemia, which is caused by dehydration and direct effects of Leptospira toxins that damages vascular endothelium and increases permeability.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…These are the most common findings reported in leptospirosis. 1,7,8,9,17,19 Hemorrhagic manifestations are characteristic of Weil disease, and are potentially fatal. Patients can develop important hemodynamic abnormalities, secondary to hypovolemia, which is caused by dehydration and direct effects of Leptospira toxins that damages vascular endothelium and increases permeability.…”
Section: Discussionmentioning
confidence: 99%
“…Fever, chills, headache, severe myalgia, conjunctival suffusion, anorexia, nausea, vomiting, and malaise usually characterizes acute leptospirosis. [7][8][9] Pulmonary involvement and acute kidney injury are the main causes of death in leptospirosis. [10][11][12] Renal involvement in leptospirosis is characterized by acute interstitial nephritis that may be associated with acute tubular necrosis.…”
Section: Introductionmentioning
confidence: 99%
“…Hemoptysis occurred in 50% of 168 cases in China between 1959 and 1960 [21] and in 13% of 115 patients hospitalized with severe leptospirosis in Brazil [22]. In the Spanish series of 26 patients with leptospirosis, 17 had respiratory symptoms, such as dyspnea (seven patients); hemoptysis with bloodstained sputum (seven patients); cough (six patients), and pleuritic chest pain (five patients) [3].…”
Section: Clinical Manifestationsmentioning
confidence: 99%
“…4 However, urban epidemics have emerged to become a major public health problem in developing countries. 7 In Brazil, epidemics of leptospirosis have been reported since the 1960s in major cities such as São Paulo, 8 Rio de Janeiro, 9 Recife, 10 and Salvador 11 following periods of heavy rainfall. Transmission presumably occurs through contact with floodwater contaminated with urine of infected rats.…”
Section: Introductionmentioning
confidence: 99%