Leptospirosis: Epidemiology and Usuel Manifestations

Mohammed, Haraji; Nozha, Cohen; Karib, H.; Fassouane, A.; Belahsen, Rekia

doi:10.3923/bj.2011.1.7

Cited by 2 publications

(2 citation statements)

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“…Initial symptoms, which may include chills, fever, headache (severe and persistent), diarrhea, or a rash [23], myalgia, malaise, prostration, retro-orbital pain, conjunctival suffusion [24], muscle tenderness and lung involvement, appear quite abruptly after an incubation period of about 10 days (range 4 to 19 days). Cases that also have other symptoms [8] such as meningitis, hemorrhage into skin and mucous membranes, jaundice, hepatorenal failure [25] and myocarditis may be misdiagnosed.…”

Section: Pathogenesismentioning

confidence: 99%

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LEPTOSPIRA: Morphology, Classification and Pathogenesis

Mohammed¹,

Nozha²,

Karib³

et al. 2011

J Bacteriol Parasitol

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Leptospirosis, caused by the pathogenic leptospires, is one of the most widespread zoonotic diseases known. Leptospirosis cases can occur either sporadically or in epidemics, Humans are susceptible to infection by a variety of serovars. These bacteria are antigenically diverse. Changes in the antigenic composition of lipopolysaccharide (LPS) are thought to account for this antigenic diversity. The presence of more than 200 recognized antigenic types (termed serovars) of pathogenic leptospires have complicated our understanding of this genus. Definitive diagnosis is suggested by isolation of the organism by culture or a positive result on the microscopic agglutination test (MAT). Only specialized laboratories perform serologic tests; hence, the decision to treat should not be delayed while waiting for the test results.

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Section: Pathogenesismentioning

confidence: 99%

“…Clinical presentations of leptopspirosis among humans range from asymptomatic infection to potentially fatal zoonosis. The majority of human infections are mild, systemic illnesses that bring headache, chills, fever, conjunctival suffusion and muscle pain [8].…”

Section: Introductionmentioning

confidence: 99%