Leptospirose révélée par une pancréatite aiguë

Diyas, Soufiane; Lezreg, Moussa; Badsi, Soufiane; Housni, Brahim

doi:10.11604/pamj.2019.34.83.15680

Cited by 2 publications

(2 citation statements)

References 6 publications

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“…6 Since then, several case series have been published in both adults and children. [7][8][9][10][11][12] In 2003, the first study involving 33 patients who died from fatal leptospirosis and submitted for autopsy, found that 12 (36.6%) had pancreatic involvement. 13 Another study in 2013 involving 20 cases found 13 cases of pancreatic damage, including four aspects of fatty necrosis.…”

Section: Discussionmentioning

confidence: 99%

Severe Acute Pancreatitis Associated with Weil’s Disease

Guechi

Guenifi

Gasmi

et al. 2023

Middle East J Dig Dis

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Leptospirosis is an emerging zoonosis of worldwide importance. Its distribution is closely linked to hydrometric conditions. It is characterized by a wide clinical range, from the subclinical form, or one with few symptoms; which resolves spontaneously, to the multi-visceral form, known as icterrohemorrhagic disease or Weil’s disease, with a lethal risk. All organs can be affected but with variable frequency. Pancreatic involvement is not well documented. We describe a 45-year-old man with Weil’s disease associated with acute necrotizing pancreatitis. The evolution was favorable but required a three-week stay in the intensive care unit.

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Section: Discussionmentioning

confidence: 99%

Severe Acute Pancreatitis Associated with Weil’s Disease

Guechi

Guenifi

Gasmi

et al. 2023

Middle East J Dig Dis

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“…It is transmitted to humans via infected animals when they come in contact with, or through, contaminated water. It is a ubiquitous disease, more commonly found in tropical climates and in areas where large reservoirs of stagnant water accumulate (3), such as lakes or water remnants from natural disasters (4) (Figure 1B), and transplacental infection is rare but possible (5).…”

Section: Introductionmentioning

confidence: 99%

Acute Kidney Injury and Acute Liver Failure in Leptospira Infection and Weil’s Syndrome

Chávez-Íñiguez

Cabrera-Aguilar

García-García

et al. 2020

jrenhep

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Leptospirosis is considered a zoonosis acquired predominantly from contaminated surfaces and water, more commonly in emerging countries with limited sanitary conditions. Leptospira in the host unleashes an immune response that explains the symptoms and clinical signs; once it reaches the kidney and liver tissue, it can manifest with alterations that lead to acute and chronic diseases in both organs. Weil’s syndrome is the best known clinical manifestation with jaundice and acute kidney injury that could lead to multiple organ failure and death. For its diagnosis, there are simplified scores such as the SPiRO score, the microbiological criteria by microscopy or serological tests; the treatment focuses on antibiotics and, if necessary, provides organic support until the infection is curtailed. The purpose of this review was to address the impact of Lep-tospira infection on the kidney and liver, the mechanisms of organ damage, the clinical presentation, and diagnosis and management of this disease.

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Leptospirose révélée par une pancréatite aiguë

Cited by 2 publications

References 6 publications

Severe Acute Pancreatitis Associated with Weil’s Disease

Severe Acute Pancreatitis Associated with Weil’s Disease

Acute Kidney Injury and Acute Liver Failure in Leptospira Infection and Weil’s Syndrome

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