Leptomyxid amoeba encephalitis: report of the first case in Argentina

Taratuto, Ana Lía; Monges, J; Acefe, J.C.; Meli, Francisco; Paredes, Abel; Martinez, A. J.

doi:10.1016/0035-9203(91)90164-t

Cited by 51 publications

(29 citation statements)

References 2 publications

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“…A review of the literature suggests that cases involving males are more prevalent. [3][4][5][6][7][8][9][10][11][12][13][14][15] Characteristic symptoms of GAE include fever, headaches, nausea, seizures, and other focal neurologic indicators, such as brain lesions. B. mandrillaris usually is found within localized areas of the brain and clustered around blood vessels.…”

Section: Introductionmentioning

confidence: 99%

“…B. mandrillaris usually is found within localized areas of the brain and clustered around blood vessels. 1,5,6,8,11,15,16 An inflammatory response subsequently is mounted in immunocompetent hosts, and amebae can be found surrounded by immune cells, such as macrophages, lymphocytes, and neutrophils. In some cases, B. mandrillaris has been mistaken for macrophages.…”

Section: Introductionmentioning

confidence: 99%

“…Infections also have caused skin lesions, and in a few cases amebae have been found in the kidneys and lungs. 4,10,[13][14][15]17,18 Hemorrhaging of organs in many clinical cases provides evidence that B. mandrillaris had been present in these locations even when amebae were not isolated from the tissue samples. Eventually, patients die of a massive central nervous system infection.…”

Section: Introductionmentioning

confidence: 99%

“…1,6,10,[15][16][17]23 Currently an immunofluorescence test using species-specific sera is the most reliable means to distinguish between the 2 amebae. In contrast to Acanthamoeba, which has been found readily in soil, water, and sewage, B. mandrillaris has never been isolated from the environment.…”

Section: Introductionmentioning

confidence: 99%

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GENOTYPING OF BALAMUTHIA MANDRILLARIS BASED ON NUCLEAR 18S AND MITOCHONDRIAL 16S rRNA GENES

Booton¹,

Carmichael²,

Visvesvara³

et al. 2003

The American Journal of Tropical Medicine and Hygiene

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Abstract. Balamuthia mandrillaris is an opportunistically pathogenic ameba that causes fatal granulomatous amebic encephalitis (GAE) in vertebrates. Previous phylogenetic analyses that included the sequence of a single nuclear small subunit ribosomal RNA gene (18S or ssu rDNA) from this ameba suggested that Balamuthia is closely related to Acanthamoeba, another opportunistically pathogenic amebic genus, which includes multiple ssu rDNA genotypes. We tested whether this also is true for Balamuthia. The nuclear ssu rDNA from 4 isolates and the mitochondrial ssu rDNA from 7 isolates of B. mandrillaris have been sequenced. No variation in the nuclear rDNA sequences and low levels of variation in the mitochondrial rDNA were found. Both gene sequences were consistent with a single genotype for B. mandrillaris. The mitochondrial sequences of B. mandrillaris are unique and should be useful for development of genus-specific diagnostic probes for use with clinical, environmental, and archived specimens.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

GENOTYPING OF BALAMUTHIA MANDRILLARIS BASED ON NUCLEAR 18S AND MITOCHONDRIAL 16S rRNA GENES

Booton¹,

Carmichael²,

Visvesvara³

et al. 2003

The American Journal of Tropical Medicine and Hygiene

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“…Balamuthia mandrillaris, inicialmente identificada como causa de encefalitis en mandriles, ha sido reconocida como patógeno en humanos desde 1993 1 . Desde esa fecha, más de 100 casos han sido reportados en la literatura médica, provenientes de Australia, los Estados Unidos de Norte América, Japón, República Checa, y Latinoamérica, incluyendo Argentina, Brasil, México, Perú y Venezuela [2][3][4][5] . La enfermedad es muy poco reconocida en Europa y en el Sur Este de Asia 6 .…”

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