Leptin and Adiponectin Responses in Overweight Inactive Elderly following Resistance Training and Detraining Are Intensity Related

Fatouros, Ioannis G.; Tournis, Symeon; Leontsini, Diamanda; Jamurtas, Athanasios Z.; Sxina, M.; Θωμάκος, Πέτρος; Manousaki, Mina; Douroudos, Ioannis; Taxildaris, Kyriakos; Mitrakou, Asimina

doi:10.1210/jc.2005-0261

Cited by 206 publications

(272 citation statements)

References 59 publications

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“…These results are in agreement with previous studies (11,19,38). Based on the negative correlation between adiponectin and body fat percentage found in the present study and to reduce the risks of atherosclerosis by reducing body fat, it could be suggested that patients and normal sedentary individuals need to participate in endurance-and resistance-training programmes that lead to loss of body weight and fat reduction.…”

Section: Discussionsupporting

confidence: 93%

“…In the present study, adiponectin concentration did not change following 12 weeks of circuit weight training at 50-60% 1-RM, which is a low-intensity protocol. Our findings support those of Klimcakova et al (20) and the low-intensity protocol of Fatouros et al (19). Therefore, it can be concluded that changes in adiponectin in response to resistance training might be intensity related.…”

Section: Discussionsupporting

confidence: 92%

“…Few resistance-training studies that have investigated changes in adiponectin have also reported conflicting results (19)(20)(21). Klimcakova et al (20) reported no changes in adiponectin concentration in response to 3 months of resistance training performed thrice a week at 60-70% of 1-RM with 12-15 repetitions for each exercise (30-45 min per session).…”

Section: Discussionmentioning

confidence: 99%

“…The physiological and biochemical responses to resistance exercise are different from those exhibited in response to endurance exercise (18). There are few studies that have examined the effects of resistance training on adiponectin and insulin sensitivity (19)(20)(21) and the results are controversial. For example, recently Klimcakova et al (20) have reported no changes in adiponectin concentration in response to 3 months of resistance training, while Fatouros et al (19) investigated the effects of 6 months of resistance training with different intensities and reported significant increases in adiponectin after moderate-and high-intensity training but not after lowintensity training.…”

Section: Introductionmentioning

confidence: 99%

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Effects of resistance versus endurance training on serum adiponectin and insulin resistance index

Ahmadizad

Haghighi²,

Hamedinia³

2007

European Journal of Endocrinology

104

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Purpose: The purpose of the present study was to investigate the effects of resistance and endurance training on serum adiponectin and insulin resistance index (S I ) in healthy men. Methods: Twenty-four healthy males (age, 35-48 years) participated in the study. The subjects were randomly assigned to one of three groups: endurance training group (nZ8), resistance training group (nZ8) and control group (nZ8). Blood samples were taken in fasting state from all subjects. The experimental groups performed either endurance or resistance training 3 days a week for 12 weeks. The endurance training programme included continuous running at an intensity corresponding to 75-85% of maximal heart rate, while resistance training consisted of four sets of circuit weight training for 11 stations and at an intensity corresponding to 50-60% of one-repetition maximum. The maximum numbers of repetitions in each station was 12.Results: There were significant negative correlations between serum adiponectin and body fat percentage, waist-to-hip ratio, body mass index and the insulin resistance index at baseline, whereas changes in response to training were not significantly correlated. Both endurance and resistance training resulted in a significant decrease in the S I in comparison with the control group. However, serum adiponectin did not change significantly in response to resistance and endurance training. Conclusion: Endurance and resistance training caused an improvement in insulin resistance in healthy men, but this improvement was not accompanied by increased adiponectin levels.European Journal of Endocrinology 157 625-631

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Section: Discussionsupporting

confidence: 93%

Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Effects of resistance versus endurance training on serum adiponectin and insulin resistance index

Ahmadizad

Haghighi²,

Hamedinia³

2007

European Journal of Endocrinology

104

View full text Add to dashboard Cite

show abstract

“…Fatouros and colleagues 27 examined the impact of a 48-week RET program for 50 older men and compared various intensities of training. At post-test, the researchers found that leptin was reduced in each intervention group and adiponectin was increased in the high intensity intervention group only.…”

Section: Discussionmentioning

confidence: 99%

Exercise effects on adipokines and the IGF axis in men with prostate cancer treated with androgen deprivation: A randomized study

Mina

Connor²,

Alibhai³

et al. 2013

CUAJ

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Background: Androgen deprivation therapy (ADT) has significant deleterious effects on body composition that may be accompanied by unfavourable changes in adipokine levels. While exercise has been shown to improve a number of side effects associated with ADT for prostate cancer, no studies have assessed the effect of exercise on adiponectin and leptin levels, which have been shown to alter the mitogenic environment. Methods: Twenty-six men with prostate cancer treated with ADT were randomized to home-based aerobic exercise training or resistance exercise training for 24 weeks. Adiponectin, leptin, insulin-like growth factor 1 (IGF-1), insulin-like growth factor binding protein 3 (IGFBP-3) were analyzed by ELISA (enzyme-linked immunosorbent assay), in addition to physical activity volume, peak aerobic capacity, and anthropometric measurements, at baseline, 3 months and 6 months. Results: Resistance exercise significantly reduced IGF-1 after 3 months (p = 0.019); however, this change was not maintained at 6 months. At 6 months, IGFBP-3 was significantly increased compared to baseline for the resistance training group (p = 0.044).In an exploratory analysis of all exercisers, favourable changes in body composition and aerobic fitness were correlated with favourable levels of leptin, and favourable leptin:adiponectin and IGF-1:IGFBP-3 ratios at 3 and 6 months. Conclusions: Home-based exercise is correlated with positive changes in adipokine levels and the IGF-axis that may be related to healthy changes in physical fitness and body composition. While the improvements of adipokine markers appear to be more apparent with resistance training compared to aerobic exercise, these findings must be considered cautiously and require replication from larger randomized controlled trials to clarify the role of exercise on adipokines and IGF-axis proteins for men with prostate cancer.

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Progressive resistance strength training for improving physical function in older adults

Liu

Latham

2009

Cochrane Database of Systematic Reviews

813

701

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Leptin and Adiponectin Responses in Overweight Inactive Elderly following Resistance Training and Detraining Are Intensity Related

Abstract: Resistance training and detraining may alter leptin and adiponectin responses in an intensity-dependent manner. Leptin and adiponectin changes were strongly associated with RMR and anthropometric changes.

Cited by 206 publications

References 59 publications

Effects of resistance versus endurance training on serum adiponectin and insulin resistance index

Effects of resistance versus endurance training on serum adiponectin and insulin resistance index

Exercise effects on adipokines and the IGF axis in men with prostate cancer treated with androgen deprivation: A randomized study

Progressive resistance strength training for improving physical function in older adults

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