Leprosy trends at a tertiary care hospital in Mumbai, India, from 2008 to 2015

Abstract

BackgroundLeprosy remains an important cause of preventable disabilities. After the advent of multidrug therapy, new leprosy cases have come down dramatically. Despite this achievement, India, which contributes 60% of the global leprosy burden, faces some challenges to eliminate the disease, including active transmission in the community and delayed diagnosis of leprosy patients.ObjectivesThe objectives of the study were 1) to determine sociodemographic and clinical characteristics of newly diagnosed adults and children (less than 15 years) with leprosy and their trends over time (2008–2015) and 2) to describe the profile of surgical procedures among leprosy patients registered for reconstructive surgeries during 2006–2015.DesignRetrospective descriptive study was conducted involving a record review of new patients with leprosy registered in Vimala Dermatological Centre, Mumbai.ResultsA total of 578 new leprosy cases were registered in the hospital during 2008–2015. There has been a steady increase in the trend of child cases (less than 15 years) registered in the facility (from 3% in 2008 to 18% in 2015), x2=12.11, p<0.01. The majority of the patients (68%) were migrants of Uttar Pradesh and Bihar.ConclusionsTargeting children and migrants and ensuring early diagnosis and treatment initiation are essential components for leprosy elimination in an urban metropolis in India.

Leprosy in Togo: retrospective study of 2630 cases over 15 years

“…Ceci se rapproche de l'âge moyen des patients dans une précédente étude à Lomé qui était de 35 ans. Muthuvel et al en Inde avait trouvé un âge moyen de 32 ans [6] et Keita [7] au Mali avait trouvé un âge moyen de 33,8 ans. Les nouveaux cas de lèpre au Togo sont donc plus fréquents chez l'adulte jeune.…”

“…Ce taux se rapproche des 6,4% [8]en 2014 au Brésil. Il reste cependant inférieur au 10% rapporté en 2015 en Inde [6] et 14% rapporté en 2002 au Sénégal [9]. Dans une précédente étude à Lomé la capitale, 6,4% des patients étaient âgé de moins de 15 ans.…”

Current Trends in Leprosy- A Retrospective Study From a Tertiary Care Centre in Kerala

“…Previous studies also observed leprosy to be more common in middle age. 2,3 Family history of leprosy was in 1.5% of our patients. Chhabra et al observed similar history in 5.9% patients.…”

“…10% of new patients were children in a study from Mumbai during 2008-2015. 2 In another ten-year retrospective study (2003)(2004)(2005)(2006)(2007)(2008)(2009)(2010)(2011)(2012) from Kerala, 12.1% of new leprosy cases were in children. 5 Most of our patients presented in 4 th and 5 th decade of life.…”

“…1 It remains an important cause of preventable disabilities. 2 It is caused by Mycobacterium leprae, a slow growing mycobacterium. 3 Ridley and Jopling proposed a five group classification of leprosy based on clinical, histological, immunological and bacteriological findings.…”