Leprosy in the Bible

Grzybowski, Andrzej; Nita, Małgorzata

doi:10.1016/j.clindermatol.2015.10.003

Cited by 15 publications

(4 citation statements)

References 20 publications

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“…[1] It has been historically associated with ancient biblical references and has been recognised as a neglected tropical disease (NTD) by the World Health Organization (WHO). [2,3] Notably, leprosy stands as a significant infectious cause of disability in the developing world. [4] The disease is primarily transmitted through droplet spread and typically manifests cutaneous and peripheral neurological signs.…”

Section: Researchmentioning

confidence: 99%

Characteristics, clinical manifestations and management of leprosy in KwaZulu-Natal, South Africa: A 20-year retrospective study

Sons,

Mkhize,

Dlova

et al. 2024

S Afr Med J

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Background. Although leprosy, a neglected tropical disease, has been eliminated (<1 case per 10 000 population) in South Africa (SA) since 1926, according to the World Health Organization, new cases continue to be reported. The management of leprosy poses several challenges, including patient adherence, education and insufficient training of healthcare practitioners. Objectives. To describe the biographical profile, clinical manifestations and treatment outcomes in patients with leprosy in KwaZulu-Natal Province. Methods. This retrospective study aimed to analyse the clinical data of leprosy patients in SA from 2002 to 2022. Data collected included patient demographics, comorbidities, cutaneous and neurological manifestations of leprosy, complications, treatment and adverse reactions. Descriptive statistics were used to summarise the data. Results. The study analysed the clinical data of 194 leprosy patients from 2002 to 2022. The majority of patients were male and middle aged, with a disproportionate representation of black South Africans. Regarding socioeconomic status, 80% were unemployed and 40% were social grant recipients. Most cases were clustered in urban centres and diagnosed at secondary care facilities, with 15% being HIV positive. The majority of patients (90%) were classified as having multibacillary leprosy. Common symptoms included upper respiratory tract involvement, hair loss and painful nerves, with the face and limbs being most frequently affected. Cutaneous morphology predominantly included plaques and hypopigmented patches, while neurological signs included ulnar nerve tenderness, muscle weakness and sensory deficits. Debilitating neurological complications were found in one-fifth of patients. Despite initiation of multidrug therapy in most patients, a significant proportion (27.3%) did not complete the full course of treatment, and treatment reactions were noted in 33.5% of patients. Conclusion. These findings emphasise the urgent need for enhanced patient and healthcare worker education, particularly in primary healthcare settings, to improve adherence to treatment, advocate for prophylactic measures and prevent new cases. Achieving leprosy-free status in SA requires the collaboration of many role-players to address these challenges and improve healthcare practices.

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Section: Researchmentioning

confidence: 99%

Characteristics, clinical manifestations and management of leprosy in KwaZulu-Natal, South Africa: A 20-year retrospective study

Sons,

Mkhize,

Dlova

et al. 2024

S Afr Med J

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“…Leprosy and skin diseases resembling it meant that a person was deemed as culturally impure (as per the Law of Purity), leading to total exclusion from one's community. When diagnosed with this condition, a person was placed in a seven day quarantine then forced to abandon their family to live in the outskirts with similar people for the rest of their lives (Grzybowski and Nita, 2016). In Foucault's (1978) Discipline and Punish, discrimination against those suffering from leprosy is once again brought up, but in the feudal French context in which similar bans on social life and in-town or city living were carried out.…”

Section: Digital-based Surveillancementioning

confidence: 99%

Discourse, Antagonisms, and Identities during the COVID-19 Pandemic

Anisin¹

2022

rccs

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This study utilizes theory from the Essex School of Ideology and Discourse Analysis (IDA) and investigates speeches and statements made by high-ranking European Union officials from the European Commission as well as policy documents. The inquiry reveals that antagonistic language was used to justify the tracking and tracing of civilians through the articulation of an empty "track and trace" signifier and the articulation of new identities premised on the vaccinated and non-vaccinated. Policy makers articulated new ideas surrounding a regime of truth and a common "people" while simultaneously negating opponents to pandemic policies by articulating floating signifiers, including xenophobia, disinformation, and populism. The exercise of power in health policies during the pandemic functioned according to logics similar to those employed in traditional political domains.

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“…The disease is highly contagious, but few people develop the disease once there is natural resistance to the bacillus [65]. This is one of the oldest diseases known to affect humankind, with reports in the Bible [67].…”

Section: Leprosymentioning

confidence: 99%

Neglected Tropical Diseases with an Impact on Kidney Function

Silva¹,

Jereissati²,

Neri³

et al. 2018

Current Topics in Tropical Emerging Diseases and Travel Medicine

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Neglected tropical diseases are a group of infectious diseases caused by infectious and parasitic agents that occur in a large part of the world affecting millions of people and can complicate matters with serious organ damage. The kidneys can be affected in many of these diseases, including Chagas disease, dengue, leishmaniasis, leprosy, and schistosomiasis. In this chapter, we describe the mechanisms by which the kidneys are damaged in the setting of these diseases, the clinical manifestations, and the current available treatment options. We also describe the recent novel biomarkers that are under investigation for the early diagnosis of kidney injury in the course of these diseases and the future perspectives.

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Leprosy in the Bible

Cited by 15 publications

References 20 publications

Characteristics, clinical manifestations and management of leprosy in KwaZulu-Natal, South Africa: A 20-year retrospective study

Characteristics, clinical manifestations and management of leprosy in KwaZulu-Natal, South Africa: A 20-year retrospective study

Discourse, Antagonisms, and Identities during the COVID-19 Pandemic

Neglected Tropical Diseases with an Impact on Kidney Function

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