Lepromatoid Lesion Developed in Nude Mouse Inoculated with Mycobacterium leprae

Freeze-fracture Observations of the Cell Walls and Peribacillary Substances of Various Mycobacteria

“…leprae in vivo has been successful in armadillos and nude mice (Storrs et al, 1974;Kohsaka et al, 1976) though it has been complicated sometimes by naturally occurring or contaminating mycobacteria. Among the 32 strains of 18 species of cultivable mycobacteria that we studied, no strains revealed peribacillary structures resembling those of M .…”

Combined Therapy in Leprosy

“…The few ex periments conducted so far have given con flicting results [1,8,38,41], but sup port our theory, derived from the results of our own experiments that the common hy pothesis of leprosy immunology is not in ac cordance with reality. These experiments did not provide any results which should be considered with regard to chemotherapy.…”

Acid-fast Bacilli Detected in Umbilical Codes and Skins of Human at Cases of Surgical Operation

“…Since a neonatal immunological tolerance was assumed on the basis of no inflammation around the infection focus, human fetuses of artificial abortion were studied for detection of acid-fast bacilli by chloroform collection method. As Mycobacterium l eprae became possible to isolate in nude mouse (3), I attempted to isolate the M. leprae-like acid -fast bacilli in nude mouse .…”