Abstract:Until the 1990s, the active and passive length‐tension (L‐T) curves for smooth muscle were believed to be static, with single passive tension (Tp) and maximum active tension (Ta) values for each length. However, recent studies have shown that the L‐Ta curves in airway and vascular smooth muscles can adapt to length changes. Our prior studies have shown that the L‐Tp curve in detrusor smooth muscle (DSM) is not static and can shift along the length axis as a function of strain and activation history, a trait we… Show more
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