Lemierre Syndrome as a Complication of Laryngeal Carcinoma

Colbert, Christopher M.; McCormack, Molly; Eilbert, Wesley; Bull, Lynea

doi:10.5811/cpcem.2017.12.36442

Cited by 4 publications

(4 citation statements)

References 20 publications

(25 reference statements)

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“…Lemierre’s syndrome has the following characteristics [1]: (i) follows an oropharyngeal infection;(ii) there is a presence of suppurative thrombophlebitis of the IJV with metastatic septic emboli;(iii) is usually caused by fusobacterium; and(iv) affects mainly young and previously healthy patients.…”

Section: Discussionmentioning

confidence: 99%

“…Apart from oropharyngeal infection, trauma [1], primary infections in the sinuses [2] or face [3] and head and neck, malignancies [1] can also cause IJV thrombosis.…”

Section: Discussionmentioning

confidence: 99%

“…Apart from Fusobacterium spp. , other causative bacteria include Eikenella , Proteus , Bacteroides , Peptococcus , Peptostreptococcus , Klebsiella , Streptococcus and Staphylococcus (both MSSA and MRSA) [1].…”

Section: Discussionmentioning

confidence: 99%

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A case of Lemierre-like Syndrome: internal jugular vein thrombosis secondary to Staphylococcus aureus sternoclavicular joint septic arthritis

Tey

Kuthiah

et al. 2019

Oxford Medical Case Reports

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Lemierre syndrome is the internal jugular vein (IJV) suppurative thrombophlebitis, usually secondary to oropharyngeal infection. Staphylococcus aureus is an emerging responsible pathogen. We report a unique case of IJV thrombosis secondary to methicillin-susceptible S. aureus sternoclavicular joint septic arthritis. We review the existing literature on Lemierre syndrome: its various manifestations, causative pathogens, treatment and management.

show abstract

Section: Discussionmentioning

confidence: 99%

“…Apart from oropharyngeal infection, trauma [1], primary infections in the sinuses [2] or face [3] and head and neck, malignancies [1] can also cause IJV thrombosis.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

A case of Lemierre-like Syndrome: internal jugular vein thrombosis secondary to Staphylococcus aureus sternoclavicular joint septic arthritis

Tey

Kuthiah

et al. 2019

Oxford Medical Case Reports

View full text Add to dashboard Cite

show abstract

“…It manifests as metastatic septic emboli, with a tendency to rapidly involve organs such as lungs followed by liver, spleen, kidney, joints, soft tissues, and brain [3,5]. It commonly presents with septic thrombophlebitis of the internal jugular vein and metastatic foci of infection [6]. e diagnosis of Lemierre's syndrome is based on the clinical presentation, a positive microbial culture, and a positive radiological finding.…”

Section: Introductionmentioning

confidence: 99%

Diagnosis and Management of Lemierre’s Syndrome Presented with Multifocal Pneumonia and Cerebral Venous Sinus Thrombosis

Sattar¹,

Susheela

Karki

et al. 2020

Case Reports in Infectious Diseases

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A 27-year-old female patient initially presented with fever, myalgia, sore throat that progressed to multifocal pneumonia, and cerebral sinus venous thrombosis. A combination of upper respiratory symptoms with tooth infection, positive blood culture for Fusobacterium nucleatum, computed tomography (CT) chest finding of multifocal pneumonia, and magnetic resonance imaging (MRI) finding of internal jugular vein thrombosis (IJVT) and cerebral venous sinus thrombosis (CVST) suggested Lemierre syndrome. The patient was managed with fluids, antibiotics, and anticoagulants. The patient survived and discharged from the hospital. The patient’s symptoms improved at 2 months of follow-up.

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Elderly onset atypical Lemierre’s syndrome concurrent with a rheumatoid vasculitis sacral ulcer infection: a case report

et al. 2023

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Background Typical Lemierre’s syndrome is usually secondary to an oropharyngeal infection. Recently, several cases following a primary infection site other than the oropharynx have been reported as atypical Lemierre’s syndrome; although, these primary lesions are limited to the head and neck. This is the first case potentially sequential to infectious foci outside the head and neck. Case presentation We describe an atypical Lemierre’s syndrome in a 72-year-old woman with rheumatoid arthritis, which occurred during the treatment of Streptococcus anginosus bacteremia acquired from a sacral ulcer infection related to rheumatoid vasculitis. At first, the symptoms resolved after the initial administration of vancomycin for the bacteremia caused by methicillin-resistant Staphylococcus aureus and Streptococcus anginosus that entered via a sacral ulcer. On the 8th day, the patient developed a fever of 40 °C and unexpectedly required 10 L of oxygen due to rapid deterioration of oxygenation temporarily. Immediately contrast-enhanced computed tomography was performed to investigate systemic thrombosis including pulmonary embolism. Afterward, the newly formed thrombi at the right external jugular vein, bilateral internal jugular veins, and the right small saphenous vein were detected, and apixaban was started. On the 9th day, the patient again had an intermittent fever of 39.7 °C, and continuous Streptococcus anginosus bacteremia was revealed; subsequently, clindamycin was administered. On the 10th day, she developed a left hemothorax; consequently, apixaban was discontinued, and a thoracic drain was inserted. She repeatedly had an intermittent fever of 40.3 °C, and contrast-enhanced computed tomography detected an abscess formation at the left parotid gland, pterygoid muscle group, and masseter muscle. After Lemierre’s syndrome was diagnosed in combination with the abovementioned jugular vein thrombus, clindamycin was replaced with meropenem, and vancomycin was increased. Swelling of the lower part of the left ear became prominent with delay and peaked at approximately the 16th day. The subsequent treatment course was favorable, and she was discharged on the 41st day. Conclusion Clinicians should consider Lemierre’s syndrome as the differential diagnosis of internal jugular vein thrombosis occurring during sepsis, even though an antibiotic is administered or a primary infection site is anything besides the oropharynx.

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Lemierre Syndrome as a Complication of Laryngeal Carcinoma

Cited by 4 publications

References 20 publications

A case of Lemierre-like Syndrome: internal jugular vein thrombosis secondary to Staphylococcus aureus sternoclavicular joint septic arthritis

A case of Lemierre-like Syndrome: internal jugular vein thrombosis secondary to Staphylococcus aureus sternoclavicular joint septic arthritis

Diagnosis and Management of Lemierre’s Syndrome Presented with Multifocal Pneumonia and Cerebral Venous Sinus Thrombosis

Elderly onset atypical Lemierre’s syndrome concurrent with a rheumatoid vasculitis sacral ulcer infection: a case report

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