Leisure Time Spent Sitting in Relation to Total Mortality in a Prospective Cohort of US Adults

Patel, Alpa V.; Bernstein, Leslie; Deka, Anusila; Feigelson, Heather Spencer; Campbell, Peter T.; Gapstur, Susan M.; Colditz, Graham A.; Thun, Michael J.

doi:10.1093/aje/kwq155

Cited by 521 publications

(409 citation statements)

References 48 publications

(52 reference statements)

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“…One explanation for this lack of an association may be that, in the context of other risk factors for these conditions, the risk attributable to sedentary behaviour is relatively small. This is supported by studies that examined associations between sitting and all-cause mortality in middle-aged women, which found statistically significant but small adjusted hazard ratios [HRs] (HR=1.10 29 and HR=1.34 30 for the highest level of sitting).…”

Section: Discussionmentioning

confidence: 72%

Health Care Costs Associated with Prolonged Sitting and Inactivity

Peeters¹,

Mishra²,

Dobson³

et al. 2014

American Journal of Preventive Medicine

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Background: Physical inactivity and prolonged sitting are associated with negative health outcomes. Purpose:To examine the health-related costs of prolonged sitting and inactivity in middleaged women.Methods: Australian Longitudinal Study on Women's Health participants (born 1946−1951) answered questions about time spent sitting, walking, and in moderate and vigorous leisure activities in 2001 (n=6108), 2004 (n=5902), 2007 (n=5754) and 2010 (n=5535) surveys.Sitting time was categorized as low (0−4), moderate (5−7), and high (≥8 hours/day). Physical activity was categorized as inactive (<40), low (40−600), moderate (600−1200) and high (≥1200 metabolic equivalent minutes/week). National health insurance claims data averaged over the survey year ±1 year were used to calculate annual costs (Australian Dollars [AU$]).Differences between categories in median costs were estimated using quantile regression over four surveys with bootstrapped 95% CIs. Analyses were performed in 2013. Results:In 2010, annual median costs were AU$689 (interquartile range [IQR]=274, 1541) in highly active participants, AU$741 (IQR=279, 1690) in inactive participants, AU$671 (IQR=273, 1551) in participants with low sitting time, and AU$709 (IQR=283−1575) in participants with high sitting time. The difference in median costs for inactive and highly active participants was AU$94 (CI=57, 131) after adjustment for confounders. No statistically significant associations were found between sitting time and costs. When sitting and physical activity were combined, high sitting time did not add to the inactivity-associated increased costs. Associations were consistent across normal weight, overweight, and obese subgroups. Conclusions:Physical inactivity, but not prolonged sitting, was associated with higher health-related costs in middle-aged women. 3 IntroductionPhysical inactivity is associated with numerous physical and mental health conditions and accounts for approximately 1.5%−3.0% of the total direct health care costs in developed countries.1 It is estimated that a 10% reduction in the prevalence of inactivity could potentially reduce health care expenditures by 96 million Australian Dollars (AU$) and 150 million Canadian Dollars per year in Australia and Canada (equating to 99 and 129 million U.S. Dollars, respectively). 2, 3 Despite the potential health and economic benefits, only about half the population in developed countries meet the recommended levels of physical activity. [4][5][6] In addition to inactivity, prolonged sitting is thought to be associated with negative health outcomes such as weight gain and increased risk of mortality. 7 However, the economic consequences of prolonged sitting remain unknown. Moreover, as some studies have reported interaction effects of physical activity and sedentary time in association with mortality, 8, 9 the combined effects of prolonged sitting and inactivity on direct health care costs may be more important than their individual effects.A previous study by our group found an interaction with BM...

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Section: Discussionmentioning

confidence: 72%

Health Care Costs Associated with Prolonged Sitting and Inactivity

Peeters¹,

Mishra²,

Dobson³

et al. 2014

American Journal of Preventive Medicine

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show abstract

“…In line with another study, we did not find a significant effect of physical activity on cancer mortality in women (Table 3) . However, a study reported significant effects in women but not in men (Patel et al, 2010). Because the strongest evidence for a protective effectbesides for colon cancer -is available for breast cancer (Physical Activity Guidelines Advisory Committee, 2008), stronger associations in women could be expected.…”

Section: Discussionmentioning

confidence: 99%

Impact of different domains of physical activity on cause-specific mortality: A longitudinal study

Wanner

Tarnutzer

Martin

et al. 2014

Preventive Medicine

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OBJECTIVE: To examine the associations between different domains of physical activity and all-cause, cardiovascular disease (CVD) and cancer mortality. METHODS: Participants (n=17,663, aged 16-92years) of two general population health studies conducted between 1977 and 1993 in Switzerland were included. Physical activity was assessed at baseline in the domains of commuting to work, workrelated physical activity, and leisure-time physical activity (including leisure-time activity level and sport activity). A median follow-up time of 20.2years was obtained with anonymous record linkage providing 3878 deaths (CVD: 1357; cancer: 1351). Adjusted Cox proportional hazard models were calculated. RE-SULTS: There were no significant associations between commuting and work-related physical activities, respectively, and mortality. Leisure-time activity level was associated with all-cause mortality in men ConclusionsThese results underline the public health relevance of physical activity for the prevention of CVD and cancer, especially regarding leisure-time physical activity.

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“…Independent of moderate-to vigorous-intensity physical activity (MVPA), sedentary behavior, defined as activities between 1.0 and 1.5 metabolic equivalents, is associated with increased risk of disability [1] and premature mortality [2]. Prolonged sedentary time is also linked with numerous health conditions, including cardiovascular disease [3,4], metabolic syndrome [5,6], obesity [7], and breast cancer [8].…”

Section: Introductionmentioning

confidence: 99%

Acceptability of smartphone technology to interrupt sedentary time in adults with diabetes

Pellegrini

Hoffman²,

Daly³

et al. 2015

Behav. Med. Pract. Policy Res.

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Breaking up sitting time with light-or moderate-intensity physical activity may help to alleviate some negative health effects of sedentary behavior, but few studies have examined ways to effectively intervene. This feasibility study examined the acceptability of a new technology (NEAT!) developed to interrupt prolonged bouts (≥20 min) of sedentary time among adults with type 2 diabetes. Eight of nine participants completed a 1-month intervention and agreed that NEAT! made them more conscious of sitting time. Most participants (87.5 %) expressed a desire to use NEAT! in the future. Sedentary time decreased by 8.1±4.5 %, and light physical activity increased by 7.9±5.5 % over the 1-month period. The results suggest that NEAT! is an acceptable technology to intervene on sedentary time among adults with type 2 diabetes. Future studies are needed to examine the use of the technology among larger samples and determine its effects on glucose and insulin levels.

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Leisure Time Spent Sitting in Relation to Total Mortality in a Prospective Cohort of US Adults

Cited by 521 publications

References 48 publications

Health Care Costs Associated with Prolonged Sitting and Inactivity

Health Care Costs Associated with Prolonged Sitting and Inactivity

Impact of different domains of physical activity on cause-specific mortality: A longitudinal study

Acceptability of smartphone technology to interrupt sedentary time in adults with diabetes

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