Leishmaniose cutanée à Leishmania tropica dans la région de Marrakech (Maroc) : un foyer rebelle !

Zougaghi, L.; Bouskraoui, M.; Amine, Mohamed; Akhdari, N.; Amal, S.

doi:10.1016/s1773-035x(11)70765-1

Cited by 8 publications

(6 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…31 At the level of ZMY, they also obtained a sex ratio in favour of women. 32 At the Chichaoua level, they calculated a sex ratio of 0.8. 33 Moreover, in Algiers, Algeria, a sex ratio of around 0.95 was observed, while in Tunisia, a sex ratio of 1.02 was recorded.…”

Section: Resultsmentioning

confidence: 99%

Coexistence of Cutaneous and Visceral Leishmaniasis in the Province of Moulay Yaâcoub, North-Central Morocco

2023

TJNPR

View full text Add to dashboard Cite

Leishmaniasis is an infectious disease transmitted to humans by the bite of a female sandfly. In Morocco, leishmaniasis is considered a real health concern. The aims of this study were to analyze the epidemiological situation and identify localities at risk of transmission of leishmaniasis in the province of Moulay Yaâcoub. The study was a retrospective analysis of leishmaniasis cases reported over a period of 11 years from 2005 to 2015 in Moulay Yaâcoub Province. The data were collected from the registries of the Prefectural Cell of the Moulay Yaâcoub Province Medical Delegation, Regional Directorate of Health, Fez-Meknes, and analyzed statistically. The results showed that leishmaniasis was present, with an annual average of 18.63 cases. A total of 205 cases of leishmaniasis were recorded, with 53% cutaneous leishmaniasis and 47% visceral leishmaniasis. Females were the most affected, at 53.7%, mainly by cutaneous leishmaniasis, although the difference was not statistically significant (χ 2 = 0.7, pvalue = 0.79). Cutaneous leishmaniasis affected all age groups, whereas visceral leishmaniasis affected only young people under 30. The communes most affected were Ain Chkef and Ain Kansara, and the difference between the proportions of cases detected in the different sites was statistically significant (χ2 = 96.03, p-value < 0.05). To the best of our knowledge, this is the first time such a study has been conducted in Moulay Yaâcoub Province.

show abstract

Section: Resultsmentioning

confidence: 99%

Coexistence of Cutaneous and Visceral Leishmaniasis in the Province of Moulay Yaâcoub, North-Central Morocco

2023

TJNPR

View full text Add to dashboard Cite

show abstract

“…Furthermore, our result is consistent with that of Guessouss et al [34] in the Nordic provinces of Morocco, the results of which show that the female sex is mostly affected by CL with a rate of 56%. At the level of Chichaoua, the sex ratio was observed at the order of 0.8 [35]. For VL, the distribution was marked by a sex ratio of 0.8 for females in the Province of Sefrou.…”

Section: Distribution Of Leishmaniasis Cases According To Gendermentioning

confidence: 90%

Cartography and Epidemiological Study of Leishmaniasis Disease in Sefrou Province (2007–2010), Central North of Morocco

Talbi

Khayyat

Omari³

et al. 2020

Interdisciplinary Perspectives on Infectious Diseases

View full text Add to dashboard Cite

Increasing cases of leishmaniasis disease have been reported during recent years in Sefrou Province, Central North of Morocco. This study presents the epidemiological profile of the provincial population, aims at analyzing the epidemiological profile, and in particular, spatiotemporal follow-up of all cases of leishmaniasis. It is a retrospective analysis of leishmaniasis cases recorded between 2007 and 2010. The data were analyzed by SPSS software (version 20). Over a four-year period, from 2007 to 2010, there were 62 cases of leishmaniasis, 93.12% of cases of cutaneous leishmaniasis and 6.87% of visceral leishmaniasis. The case number of leishmaniasis in the Province of Sefrou varies between 0.165% and 0.0018%. For each type of leishmaniasis, the female sex was the most affected compared to the male sex. This difference cannot be considered statistically significant (χ2 = 0.083, p value = 0.77). For cutaneous leishmaniasis, all age groups were affected with a large percentage: patients aged 0–9 years with 63.11% followed by the age group [10–19] with 24.18%. Visceral leishmaniasis mainly has affected the infant population [0–9] with 83.33%. We have not observed any association between the age classes and the leishmaniasis type (χ2 = 6.20, p value = 0.4). From a spatial point of view, the majority of cases of leishmaniasis was reported in El Menzel region (67 cases) followed by Sefrou (64 cases) and Tazouta (38 cases). There is a statistically significant relationship between the type of leishmaniasis and the studied regions (χ2 = 52; p value <0.001). The study of the epidemiological profile of leishmaniasis cases may be useful in enlightening health authorities to develop screening, treatment, and control strategies to reduce the incidence rate of the disease. Other research studies can be conducted to the dynamics of the vectors of sandflies and their ecology.

show abstract

“…Nevertheless, it may be an underestimation related to the diagnostic methods used notably if patient use substances as personal treatment. In fact; CLt was recognized endemic in various provinces of Marrakech‐Safi region (Zougaghi et al., 2011), while, CLm is endemic in arid region situated in the eastern and south‐eastern of Morocco (Ait Kbaich et al., 2017). Thus, the unusual existence of L. major in this area can be explained by the presence of vector, ( P. papatasi ), characterized by its wide geographical distribution in these arid regions (Karmaoui, 2020); moreover, Merions shawi grandis is the main reservoir of L. major in Morocco (Kholoud et al., 2018).…”

Section: Discussionmentioning

confidence: 99%

“…The province of Youssoufia remains a potential focus of leishmaniasis due to ecological and demographic factors within this province. Indeed, its semi‐arid climate favours the presence of sand fly vectors (High Planning Commission, 2018); its proximity to the main foci of CL, especially Chichaoua province (Zougaghi et al., 2011); and finally its rural character and the poverty of the local population, considered as a risk factor (Amane et al., 2022). However, in this province, local and regional authorities have not reported any autochthonous cases, according to these authorities in the prelimenary survey, only six imported cases of CL have been recorded in the last 5 years (2017–2021), distributed in particular in three localities (Jnane bouih, Lakhoualqa, El Gantour).…”

Section: Introductionmentioning

confidence: 99%

Entomological, parasitological and molecular investigations in a new focus of cutaneous leishmaniasis in Youssoufia region, Morocco

Amane,

El Mazini,

Echchakery

et al. 2023

Zoonoses and Public Health

View full text Add to dashboard Cite

Background and AimsLeishmaniasis is a neglected tropical infection caused by Leishmania parasite that affect human and animal. In Morocco, the cutaneous leishmaniasis has spread substantially to the new areas. The surveillance limited to active foci may underestimate the occurrence of cutaneous leishmaniasis (CL). This study aims to investigate the local transmission of CL in rural districts of Youssoufia province, central Morocco, as a potential focus of CL.MethodsFor this purpose, parasitological, molecular and entomological investigations were carried out in this area. Data collection concerns potential vectors and human cases. Thus, 402 patients were examined for suspected leishmaniasis lesions in three localities of the province of Youssoufia. In these same localities, 983 sand flies were collected by CDC light traps and sticky paper during one‐night per month during 6 months. These sand flies were all identified morphologically using the Moroccan identification key.ResultsThe results showed that among the 25 skin lesions detected in a population of 402 individuals, 18 were confirmed by kDNA nested PCR as CL positive patients, of which only 25% were positive by direct examination. Leishmania tropica and Leishmania major were identified as causative agents of CL in the study area. Direct parasitological examination showed a low sensitivity (27.78%), especially for L. major, although its specificity was evaluated at 100%. Regarding entomological results, both genera of the Moroccan sand fly were collected in the study area: Genus/Phlebotomus (75.28%) and Sergentomyia (24.72%). Phlebotomus (P) papatasi, the proven vector of L. major, was the most abundant species (33.98%), followed by Paralongicollum sergenti (22.58%), the confirmed vector of L. tropica; while Sergentomyia (S) minuta, P. longicuspis, S. fallax and P. kazeruni were collected with, respectively, 17.60%, 16.99%, 7.12% and 1.73%.ConclusionThis study constitutes the first report of CL in the study areas, as well as the coexistence of L. tropica and L. major in these rural localities. Local transmission of CL is highly probable, as indicated by the prevalence of the two proven vectors of L. major and L. tropica. To control the spread of this disease, our results suggest the use of highly sensitive molecular methods to detect CL cases in potential leishmaniasis foci, which will improve surveillance.

show abstract

Leishmaniose cutanée à Leishmania tropica dans la région de Marrakech (Maroc) : un foyer rebelle !

Cited by 8 publications

References 8 publications

Coexistence of Cutaneous and Visceral Leishmaniasis in the Province of Moulay Yaâcoub, North-Central Morocco

Coexistence of Cutaneous and Visceral Leishmaniasis in the Province of Moulay Yaâcoub, North-Central Morocco

Cartography and Epidemiological Study of Leishmaniasis Disease in Sefrou Province (2007–2010), Central North of Morocco

Entomological, parasitological and molecular investigations in a new focus of cutaneous leishmaniasis in Youssoufia region, Morocco

Contact Info

Product

Resources

About