Leishmaniasis dissemineted by Leishmania braziliensis in a mare (Equus cabalus) immunotherapy and chemotherapy assays

Abstract

Cutaneous disseminated lesions caused by Leishmania sp. were found in a pregnant mare (Equus cabalus) from a rural city in the State of Rio de Janeiro, Brazil. Before delivering, treatment was undertaken by immunotherapy followed by chemotherapy. Histopatology and serology were performed during treatment, as well as the biochemical characterization of the parasite (L. braziliensis) that was isolated from one of the lesions.

Parasite Genotypically Related to a Monoxenous Trypanosomatid of Dog's Flea Causing Opportunistic Infection in an HIV Positive Patient

“…L. (V) braziliensis has been recorded ever since. In other foci near the metropolitan region of Rio de Janeiro both forms (tegumentar and/or visceral) of the disease are present in humans and domestic animals, being L. (V) braziliensis and L. (L) chagasi the unique species detected until now (Oliveira-Neto et al 1986, Barbosa-Santos 1994. In such areas is not exceptional to find dogs and human beings living together in the same dwelling.…”

Infection of the equine population by Leishmania parasites

“…Molecular tools, such as PCR, followed or not by sequencing analysis, were applied for diagnosis confirmation and the identification of the infectious Leishmania species, respectively (Tables and ), even though a negative PCR result (due to a low parasite load) cannot rule out the presence of the current infection . Moreover, several studies discussed that the detection of specific anti‐ Leishmania antibodies, by DAT or by ELISA, indicates a previous contact with the parasite, whereas the presence of Leishmania DNA constitutes a confirmation of the current infection .…”

Cutaneous leishmaniosis in three horses in Spain

“…Since then, cutaneous leishmaniosis in horses, mules and donkeys has been diagnosed in both South America (Aguilar et al 1987;Falqueto et al 1987;Barbosa-Santos et al 1994) and Central America (Ramos-Vara et al 1996). In those cases where biochemical characterisation of the parasite was performed, L e i s h m a n i a b r a z i l i e n s i s was always the species identified (Falqueto et al 1987;Oliveira-Neto et al 1988;Barbosa-Santos et al 1994). In southern European countries, leishmaniosis is caused by L e i s h m a n i a i n f a n t u m, where dogs and man are the most affected hosts (Anon 1990).…”