Leishmania (Viannia) braziliensis is the main species causing cutaneous leishmaniasis in the Federal District of Brazil

Abstract

Abstract:The first autochthonous case of American cutaneous leishmaniasis was reported in the Federal District in 1980, and the species involved in this type of leishmaniasis was unknown. This study aimed to identify the species that causes the disease in the Federal District and to investigate its clinical and epidemiological aspects. Between 2000 and 2007, 71 autochthonous cases of leishmaniasis were reported in the Federal District. Leishmania species were identified by means of direct immunofluorescence reactions using monoclonal antibodies and restriction fragment length polymorphism. The species of 40 (56.33%) out of 71 samples were identified. Thirty-six (90%) were identified as Leishmania (Viannia) braziliensis and four (10%) were identified as Leishmania (Leishmania) amazonensis. In this area, the disease had clinical and epidemiological characteristics similar to those found in other Brazilian regions.

Cutaneous Leishmaniasis Following Local Trauma: A Case Report

“…The patient developed CL lesion at the same site of the induced trauma, with short incubation period, as stated in literature [3,11]. The Leishmania species responsible for such lesions is already expected to be Leishmania (Viannia) braziliensis, since it is the most prevalent species in Brazil and in Distrito Federal [4,17].…”

The influence of treatment on the development of leishmaniasis recidiva cutis: a 17‐year case–control study in Midwestern Brazil

“…In the Americas, L. (V.) braziliensis, L (L.) amazonensis, L. (V.) panamensis and L (V.) guyanensis infections have also been documented to cause the disease . In Midwestern Brazil, the predominant species involved in ACL are L. (V.) braziliensis and L. (L.) amazonensis , and the former is responsible for 90% of the cases . Autochthonous ACL caused by other species has not been described in our region…”

“…1,2,4,7,8 In Midwestern Brazil, the predominant species involved in ACL are L. (V.) braziliensis and L. (L.) amazonensis, 9 and the former is responsible for 90% of the cases. 10 Autochthonous ACL caused by other species has not been described in our region. 9 The incidence of LRC in patients with ACL remains unknown.…”

“…This species was expected to be the causative agent because it is the dominant species in the study area, thereby ensuring probable homogeneity between the groups. 10 Llanos-Cuentas et al demonstrated that L. (V) braziliensis and L. (V.) peruviana are correlated with a reduced chance of cure after treatment with sodium stibogluconate. 23 The authors indicated that 95% of treatment failures occurred within 3 months after treatment.…”

“…In our study, L. (V.) braziliensis was identified as the causative agent in all the cases investigated. This species was expected to be the causative agent because it is the dominant species in the study area, thereby ensuring probable homogeneity between the groups . Llanos‐Cuentas et al .…”