Leiomyosarkome

Baumann, A.; Schweiger, S; Schweiger, Wolfgang; Tomka, M.; Thalhammer, M.; Baumann, G; Cohnert, Tina

doi:10.1007/s00772-008-0610-z

Cited by 2 publications

(3 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Commonly, these tumors are negative for protein S-100 and neuron-specific enolase. However, expression of protein S-100, Leu 7, and epithelial membrane antigen have also been reported for leiomyosarcoma [2]. Morphology and immunohistochemical staining of the present case are in line with these features and thus confirm the diagnosis of leiomyosarcoma (Fig.…”

Section: Discussionsupporting

confidence: 87%

“…Also due to the low incidence of this tumor, no adjuvant or neoadjuvant chemotherapy or radiotherapy regimen has been established for vascular leiomyosarcoma [2, 4, 7]. Up to date, radical resection aiming at complete local tumor clearance remains the primary treatment modality for patients with resectable vascular leiomyosarcoma and may achieve a favourable outcome [2–4, 7, 8, 10].…”

Section: Discussionmentioning

confidence: 99%

“…Up to date, radical resection aiming at complete local tumor clearance remains the primary treatment modality for patients with resectable vascular leiomyosarcoma and may achieve a favourable outcome [2–4, 7, 8, 10]. Considering the local recurrence in our patient, an adjuvant radiation therapy should have been considered.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Portal vein leiomyosarcoma: a case report and review of the literature

et al. 2016

View full text Add to dashboard Cite

BackgroundLeiomyosarcoma of vascular smooth muscle is a very rare entity. A fair number of cases of vascular leiomyosarcomas have been reported, and the vast majority of these tumors arose from the inferior vena cava.Case PresentationWe report the case of a 71-year-old female patient who presented with recurrent upper abdominal pain. A CT-scan demonstrated a heterogenous mass in the liver hilum. Liver function tests and hematology parameters as well as the tumor markers were normal. Due to the unclear diagnosis a percutaneous biopsy of this mass was performed and revealed leiomyosarcoma. The patient was treated by a right sided hemihepatectomy with portal vein reconstruction and an end-to-side hepatico-jejunostomy. Final histology confirmed complete (R0) resection of a moderately differentiated leiomyosarcoma of the portal vein. After complete (R0) resection of the lesion, the patient remained without any signs of tumor recurrence for a total of 36 months until detection of an unresectable local recurrence. After surgical re-exploration the patient was finally referred to palliative radiotherapy.ConclusionVascular leiomyosarcoma of the portal vein is an extremely rare tumor entity. We have described a case with no evidence-based neo/adjuvant treatment options, where aggressive surgery achieved a tumor-free margin (R0), performed in a specialized center for sarcoma and hepatobiliary surgery.

show abstract

Section: Discussionsupporting

confidence: 87%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Portal vein leiomyosarcoma: a case report and review of the literature

et al. 2016

View full text Add to dashboard Cite

show abstract

Primary leiomyosarcoma of the venous vessel wall

Bode¹,

Wolter²

2014

Phlebologie

View full text Add to dashboard Cite

ZusammenfassungLeiomyosarkome machen mit nur 6 % einen kleinen Bereich der Weichteiltumore aus. Davon sind ca. 20 % gefäßassoziiert und vorwiegend im Bereich der Vena cava inferior beschrieben (1–4). Es handelt sich um einen äußerst aggressiven Tumor, der insbesondere an der unteren Extremität unspezifische Beschwerden bereitet. Primär bei nicht vorlie-gender Metastasierung ist die komplette Resektion des Tumors mit Sicherheitsabstand die Therapie der Wahl, die das Langzeitüberleben der Patienten positiv beeinflusst (2, 5, 6). Jedoch mehr als 50 % der Patienten haben bereits bei Diagnosestellung pulmonale oder hepatische Metastasen (1–3). Im Allgemeinen ist eine interdisziplinäre Zusammenarbeit von den Chirurgen, Pathologen und Onkologen sowie Radiologen gefordert.Dieses Fallbeispiel beschreibt einen 74-jährigen, männlichen Patienten mit einer seit etwa einem Jahr bestehenden lokalen Schwel-lung am proximalen linken Unterschenkel. Mit Hilfe eines Schnellschnittverfahrens konnte histopathologisch ein Leiomyosarkom mit mäßiger Differenzierung nachgewiesen werden. Es erfolgte die radikale Tumorexzision mit erfolgreicher R0-Resektion.

show abstract

Leiomyosarkome

Cited by 2 publications

References 12 publications

Portal vein leiomyosarcoma: a case report and review of the literature

Portal vein leiomyosarcoma: a case report and review of the literature

Primary leiomyosarcoma of the venous vessel wall

Contact Info

Product

Resources

About