Leiomyosarcoma of urinary bladder in a Shih Tzu dog

Abstract

A 10-year-old intact male Shih Tzu dog presented with hematuria. Double-contrast cystography revealed a polypoid filling defect at the apex of the urinary bladder.Ultrasonography revealed a heterogeneously hypoechoic intramural mass with minimal vascular flow beneath the submucosal layer. After partial cystectomy, a well-demarcated bladder leiomyosarcoma was diagnosed on histopathology. The patient was alive and well without any clinical signs, recurrence, or metastasis at the 29-month follow-up after the surgical removal of the bladder mass. Leiomyosarcoma should be considered as a differential diagnosis if mass-like lesions are observed in the urinary bladder, although this type of malignancy is rare in canines. Histopathological confirmation is important for predicting prognosis and determining further medical plans.

Obstrução Ureteral Unilateral Por Neoplasia Mesenquimal Em Um Canino - Relato De Caso

“…Os fibrossarcomas são neoplasias malignas, invasivas, e em aproximadamente 25% dos casos ocorre metástase por via hematógena (RASKIN e MEYER, 2012). Já os leiomiossarcomas são neoplasias mesenquimais malignas que surgem das células musculares lisas (PARK et al, 2022). Em cães, o leiomiossarcoma é considerado de crescimento lento, raramente metastático e recidivante (ALVES et al, 2020;MEUTEN, 2016).…”

A Systematic Review of Canine Cystectomy: Indications, Techniques, and Outcomes

“…Partial cystectomies were initially described in 1996 by Stone et al for 11 dogs with bladder neoplasia [ 23 ]. There have subsequently been multiple reports of dogs receiving partial cystectomies for treatment of UC, leiomyoma, leiomyosarcoma, hemangiosarcoma, and non-neoplastic conditions [ 14 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 ].…”

“…Two dogs with rhabdomyosarcoma were euthanized at 5 and 7 months postoperatively due to local recurrence and pulmonary metastasis, respectively [ 15 , 23 ]. Single cases of dogs with primary bladder hemangiosarcoma and leiomyosarcoma treated with partial cystectomy as a sole therapy have been reported, and the dogs were alive at 9 and 29 months postoperatively, respectively [ 14 , 26 ].…”