Leiomyosarcoma of the Vulva Mimicking as Chronic Bartholin Cyst: A Case Report

Abstract

Smooth muscle neoplasms of the vulva are rare, and when localized in the Bartholin’s gland, it can be mistaken as a benign lesion leading to a delay in diagnosis. We report a case of leiomyosarcoma of the Bartholin’s gland in a 63-year-old postmenopausal woman, which clinically mimicked a chronic Bartholin’s gland cyst. This case report emphasizes the importance of suspecting malignancy in any vulvar lesion in women of postmenopausal age, despite its location and asymptomatic appearance. A prompt, careful evaluation with adequate clinical judgment will help to manage such cases efficiently.

Vulvar Leiomyosarcoma in Pregnancy

“…This case is the first case of vulvar leiomyosarcoma showing a rapid increase in size during pregnancy reported in the Gulf region. The literature review revealed few documented cases of leiomyosarcoma located in the female genital tract [1][2][3][4][5][6][7].…”

“…Vulvar sarcomas are rare representing 1-3% of all malignancies arising in the vulva. They are of a mesenchymal origin and the most common types of vulvar sarcomas are leiomyosarcoma, rhabdomyosarcoma, liposarcoma, angiosarcoma, malignant peripheral nerve sheath tumor, malignant fibrous histiocytoma, and epithelioid sarcoma [1][2][3][4].…”

The Value of Preoperative Diagnosis in Leiomyosarcoma of the Vulva

“…We read with great interest the article by Saquib et al, entitled: "Leiomyosarcoma of the Vulva Mimicking as Chronic Bartholin Cyst: A Case Report", which was recently published in the Oman Medical Journal . 1 Firstly, we would like to congratulate the authors who have nicely described a case of asymptomatic leiomyosarcoma of the vulva mimicking chronic Bartholin gland cyst.…”

Letter in Reply: Leiomyosarcoma of the Vulva Mimicking as Chronic Bartholin Cyst: A Case Report

“…We appreciate the author’s positive comments about our article published in the July 2020 issue of the Oman Medical Journal . 1 , 2 …”

“…The histomorphological features and immunoprofile were consistent with leiomyosarcoma grade 2, according to the French Federation of Cancer Centers Sarcoma Group grading system. 2 , 5 …”