Leiomyosarcoma of the Scalp in a Newborn

Heieck, John J.

doi:10.1001/archderm.1970.04000080085017

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1973

2001

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Cited by 12 publications

(1 citation statement)

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“…Nur vereinzelt konnten die Befunde größerer Patientenkollektive retrospektiv ausgewertet werden [2,4,13]. Bei der Altersverteilung herrscht Einigkeit darüber, dass die oberflächlichen Leiomyosarkome in jedem Alter auftreten können, vereinzelt sogar auch bei Kindern oder Neugeborenen [7,10]. Die Frage, in welchem Lebensabschnitt die Leiomyosarkome der Haut am häufigsten entstehen, wird hingegen unterschiedlich beurteilt.…”

Section: Diskussionunclassified

Kutanes Leiomyosarkom

Wagner¹,

Barghorn²

2001

Akt Dermatol

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Section: Diskussionunclassified

Kutanes Leiomyosarkom

Wagner¹,

Barghorn²

2001

Akt Dermatol

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Leiomyosarcoma of the skin and subcutaneous tissue

Fields

Helwig

1981

Cancer

328

304

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In a study of 65 primary cutaneous leiomyosarcomas and 15 primary superficial subcutaneous leiomyosarcomas, tumors occurred at any age but were more common in middle age and most common on the extremities. They developed as solitary painful or tender intracutaneous or subcutaneous nodules. Microscopically, the cutaneous leiomyosarcomas consist of a poorly delineated proliferation of spindle-shaped atypical myomatous cells arranged in interlacing fascicles which merge into collagenous stroma. Subcutaneous leiomyosarcomas are more sharply circumscribed and typically include a vascular pattern. About 40% of the cutaneous leiomyosarcomas recurred, but none metastasized despite a high mitotic frequency and marked cytologic atypia. Among the 12 patients with subcutaneous leiomyosarcomas, one-half of the tumors recurred and one-third eventuated in metastasis or tumor-related death. Cutaneous leiomyosarcomas have a relatively benign biologic course and may be excised conservatively, but are less likely to recur if the local excision is wide enough to require a skin graft for closure of the surgical defect. For primary subcutaneous leiomyosarcoma, early wide local excision with adequate clear histologic borders constitutes rational treatment.

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Tumoren der Haut

Pinkus

Mehregan

1973

Spezielle Pathologische Anatomie

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Leiomyosarcoma of the Scalp in a Newborn

Cited by 12 publications

References 9 publications

Kutanes Leiomyosarkom

Kutanes Leiomyosarkom

Leiomyosarcoma of the skin and subcutaneous tissue

Tumoren der Haut

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