Leiomyosarcoma of the Female Breast: Report of a Case

Abstract

Sarcomas of the breast account for less than 1% of breast tumors. Leiomyosarcoma is an extremely rare form of primary breast sarcoma. We presented here a case of primary leiomyosarcoma of the breast in a 44-year-old woman. We present a case of primary leiomyosarcoma of the breast in a middle-aged female in whom fine-needle aspiration cytologic features uneventful.

Primary leiomyosarcoma of the breast: A case report and literature review

“…Breast leiomyosarcoma is an uncommon type of cancer with unclear etiology. These tumors may develop from stromal mesenchymal cells or the smooth muscle cells lining blood vessels [4] , [5] .…”

“…IHC analysis is often used to confirm the diagnosis. Leiomyosarcomas will be positive for desmin, smooth muscle actin, and vimentin and negative for epithelial markers, cytokeratin, and S-100 [4] , [7] , [16] . The usual tumor, nodes, and metastases (TMN) classification for breast malignancy is used for the clinical staging of leiomyosarcomas [7] .…”

“…The treatment of breast sarcomas follows the same principles as treatments for sarcomas of extremities [4] , [19] . Early-stage cases are surgically treated via excision or mastectomy [7] .…”

Metastatic malignant melanoma from anorectum presenting as an isolated breast tumor: A case report and literature review

“…[ 13 ] The breast of primary leiomyosarcoma is rare, but not unexpectedly, reported. [ 14 , 15 ] It is worth noting that primary lymphoma is uncommon in the breast, but it is not accidental. It has a wide range of clinical and microscopic manifestations, including anaplastic large cell lymphoma, a well-known simulant of epithelial tumors.…”