Leiomyosarcoma of the colon in an infant. A case report and review of the literature

Posen, J; Bar-Maor, J.A.

doi:10.1002/1097-0142(19831015)52:8<1458::aid-cncr2820520820>3.0.co;2-k

Cited by 25 publications

(3 citation statements)

References 8 publications

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“…The youngest patient to have a colonic LMS was a 26-day-old boy [11]. LMSs were also found in an 83-year-old woman and an 82-year-old man [12] (Fig. 1).…”

Section: Age and Sex Distributionmentioning

confidence: 99%

Tumors of the Appendix and Colon

et al. 2000

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This collective review includes all available case reports of smooth muscle (stromal) tumors of the appendix and large intestine in the world literature. When compiling this review, we endeavored to examine cumulative as well as recently collected data on both benign and malignant smooth muscle tumors spanning the period 1875 to 1996. In total, there were reports of 331 leiomyomas (LMs) and 263 leiomyosarcomas (LMSs). The peak age of incidence of LM was 30 to 39 years, and the peak age of incidence of LMSs was 50 to 59 years. The female/male ratio was slightly higher for LM, and the male/female ratio was higher for LMS. The descending colon and sigmoid colon were the most common sites of both benign and malignant smooth muscle tumors. The growth of LMs most often occurred extraluminally, whereas LMSs tended to grow within the lumen of the colon. With both tumor types pain was the most frequent presenting complaint, followed less commonly by complaints of a palpable mass or gastrointestinal bleeding. LMSs tended to be larger at diagnosis than LMs, though the duration of symptoms for both types of tumor was most often reported to be between 1 month and 1 year. Finally, LMSs were found to metastasize mo

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“…The youngest patient to have a colonic LMS was a 26-day-old boy [11]. LMSs were also found in an 83-year-old woman and an 82-year-old man [12] (Fig. 1).…”

Section: Age and Sex Distributionmentioning

confidence: 99%

Tumors of the Appendix and Colon

et al. 2000

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“…Leiomyosarcoma is the most common nonepithelial gastrointestinal malignancy [3]. A tumor of adult life, it is seen most commonly in the fifth and sixth decades, although instances have occurred in infants and children [13]. It occurs most frequently in the stomach followed by the small bowel, and less commonly in the large intestine [3,13], and may arise from the smooth muscle of the muscularis propria, muscularis mucosa, or blood vessels.…”

Section: Discussionmentioning

confidence: 99%

“…A tumor of adult life, it is seen most commonly in the fifth and sixth decades, although instances have occurred in infants and children [13]. It occurs most frequently in the stomach followed by the small bowel, and less commonly in the large intestine [3,13], and may arise from the smooth muscle of the muscularis propria, muscularis mucosa, or blood vessels. Anal leiomyosarcomas, in addition, may originate from the arrectores pilorum muscles of the subcutis [5].…”

Section: Discussionmentioning

confidence: 99%

Leiomyosarcoma of the anus treated with sphincter‐preserving surgery and radiation therapy

Minsky¹,

Rich²,

Mies³

1986

Journal of Surgical Oncology

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Conservative management of anal leiomyosarcoma

Minsky

Cohen

Hajdu

1991

Cancer

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Leiomyosarcomas of the large intestine are unusual neoplasms, comprising less than 0.1% of all malignancies of the colon and rectum. Six cases of leiomyosarcoma of the anus have been reported. The optimal treatment for this neoplasm is not known. The standard surgical approach is abdominoperineal resection. The authors report the seventh case of this rare neoplasm and outline its treatment using local excision and iridium 192 brachytherapy in an attempt to preserve the anal sphincter. In selected patients, conservative surgery followed by radiation therapy may be an alternative to radical surgery, with the goals of local control of the disease and anal sphincter preservation. However, more experience is needed before this approach could be recommended routinely.

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Leiomyosarcoma of the colon in an infant. A case report and review of the literature

Abstract: A rare case of leiomyosarcoma of the sigmoid colon in a 7‐week‐old infant presenting with signs of intestinal obstruction followed by colonic perforation and peritonitis is reported, and the literature pertaining to childhood colorectal leiomyosarcoma is reviewed.

Cited by 25 publications

References 8 publications

Tumors of the Appendix and Colon

Tumors of the Appendix and Colon

Leiomyosarcoma of the anus treated with sphincter‐preserving surgery and radiation therapy

Conservative management of anal leiomyosarcoma

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