Leiomyosarcoma of great saphenous vein localised to the calf

Abstract

We present the case of a 76-year-old man with a 2-month history of mildly tender swelling in the right calf for which he had an initial excision and then a wide local excision followed by a split skin graft because the initial histopathology confirmed that there was a Grade I leiomyosarcoma of great saphenous vein. A simple lump in the lower limb could be a malignant vascular tumour and should always be considered in the list of differential diagnosis of a lump in the lower limb.

Great saphenous vein leiomyosarcoma mimicking thrombosed aneurysm: A case report and review of the literature

“… 11 The first case of LMS of the inferior vena cava was reported in 1871 by Perl Tara. 12 , 13 The GSV is the most frequent site of origin of LMSs in the lower extremities, 14 with <50 cases reported since it was first described by Aufrecht 15 in 1868. The size of VLMSs can vary greatly, with reported diameters ranging from 10 to 120 mm (mean, ∼43 mm).…”

“… 22 , 24 Evidence supports the use of radiotherapy for the local management of soft tissue sarcomas in general, especially for larger lesions, 12 , 25 and for high-grade tumors. 14 For smaller soft tissue sarcomas measuring <5 cm, adjunctive radiotherapy might not be necessary due to their significantly lower recurrence rate compared with that of larger lesions 8 …”