Léiomyomes multiples traités par nifédipine

Laporte, M; Achten, G; Gheeraert, Patrick; Lowy, Martin T.; Vokaer, Alain

doi:10.1159/000249478

Cited by 2 publications

(1 citation statement)

References 8 publications

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“…Leukonychia in AA is always true leukonychia, which means it is due to intrinsic matrix abnormalities: histologically odd-appearing parakeratosis with perinuclear vacuolization and keratohyaline granules are found in the intermediate and ventral nail plates. Keratin fibers have also been found dissociated, irregularly aligned, and fragmented on electron microscopy [34,35]. These focal abnormalities reflect visible light, preventing visualization of the underlying vascularized nail bed and making that area appear white.…”

Section: Leukonychiamentioning

confidence: 99%

Alopecia Areata of the Nails: Diagnosis and Management

Pelzer,

Iorizzo

2024

JCM

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Background: Alopecia areata (AA) is a common form of non-scarring alopecia characterized by acute hair loss. Nail involvement, though not always present, can occur in AA patients. Nail changes are more frequent in severe forms of AA and in children. Methods: Literature related to nail changes in AA was comprehensively reviewed after a search on the PubMed database without time restrictions in order to identify common clinical presentations and associated factors to aid clinicians with the correct evaluation and management of these dystrophies. Results: Nail changes in AA include pitting, trachyonychia, leukonychia, red lunula, and miscellaneous alterations such as longitudinal ridging and brittle nails. Nail changes are usually asymptomatic but, nevertheless, sometimes cosmetically disfiguring and can be associated with a reduced quality of life and impaired daily activities. Conclusions: Nail changes in AA may precede or follow hair loss and can occur as an isolated finding. Diagnosis may require a biopsy for definitive identification. Spontaneous improvement is possible, particularly in children, and treatment is not always necessary. Further research is, however, needed to establish a consensus on treatment approaches according to age and severity.

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Section: Leukonychiamentioning

confidence: 99%

Alopecia Areata of the Nails: Diagnosis and Management

Pelzer,

Iorizzo

2024

JCM

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Extensive multiple piloleiomyoma in the submental region treated successfully by surgery and reconstruction with a submental perforator flap

Matsushita

Ishihara

Takeda

et al. 2009

Clinical and Experimental Dermatology

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Piloleiomyoma is a benign tumour originating in the smooth muscles of the arrector pili muscle in the skin. The lesions are often sensitive to touch, cold and emotional disturbance. We present a patient with multiple piloleiomyoma (MPL) of the submentum who underwent reconstructive surgery using a submental perforator flap. The result was excellent and there were no postoperative complications. MPL of the submental region is relatively rare; to our knowledge, ours is the first report of MPL treated successfully with a submental perforator flap.

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Léiomyomes multiples traités par nifédipine

Abstract: The authors describe a new case of multiple cutaneous leiomyomata: a female patient aged 33 presents lesions in hundreds causing severe pain. The subjective symptoms are highly improved by the calcium antagonist nifedipine.

Cited by 2 publications

References 8 publications

Alopecia Areata of the Nails: Diagnosis and Management

Alopecia Areata of the Nails: Diagnosis and Management

Extensive multiple piloleiomyoma in the submental region treated successfully by surgery and reconstruction with a submental perforator flap

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