Leiomyomas of the lower respiratory tract.

White, Stuart; Ibrahim, N. B. N.; Forrester-Wood, C P; Jeyasingham, K.

doi:10.1136/thx.40.4.306

Cited by 106 publications

(77 citation statements)

References 13 publications

(3 reference statements)

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“…At the thoracic level, this tumor can originate from the esophagus, bronchi or vascular structures; therefore, its location can be mediastinal, pulmonary parenchyma, chest wall, diaphragm and pleural cavity. 3,[5][6][7][8] Primary leiomyoma of the chest wall is extremely rare, and so far only a few cases have been reported. 4,6 Inberg et al 7 described two cases of primary leiomyoma originated from intercostal space.…”

Section: Discussionmentioning

confidence: 99%

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Primary Leiomyoma of The Chest Wall

Tuncer¹,

Sulu²,

Aksoy³

et al. 2011

Solunum

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ÖZET ABST RACTThirty-eight-year-old female patient presented with 3 months history of chest pain. Chest x-ray showed a mass of 836 cm in size in the right middle and lower lung fields. Computed tomography of the thorax demonstrated a cystic lesion in the right lung. A right thoracotomy was performed. The mass originated from the chest wall with its base on the 6th rib. The tumor was excised and partial costal resection was performed. The macroscopic features of the tumor were a soft, smoothly surfaced white mass of 83534 cm in size. Histopathologically, the tumor consisted of packets and bundles of smooth muscle fibers without significant celluler pleomorphism, necrosis and mitotic activity. Immunohistochemically, smooth muscle actin and vimentin was positive but S-100 protein was negative in tumour cells. No pathological finding was detected during follow-up.

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Section: Discussionmentioning

confidence: 99%

“…1 A few smooth muscle tumors arising from mediastinum, lung or diaphragm have been reported in the thorax. 2,3 However, leiomyoma originating from the chest wall is extremely rare. 2,4 We present a case with primary leiomyoma of the chest wall.…”

Section: Introductionmentioning

confidence: 99%

Primary Leiomyoma of The Chest Wall

Tuncer¹,

Sulu²,

Aksoy³

et al. 2011

Solunum

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“…The diagnosis of pulmonary leiomyoma in a 38-year-old man is fitting with the mean age at presentation of 35-40 years, although cases have been reported at all ages [1,2]. Fig.…”

Section: Discussionmentioning

confidence: 99%

“…Localization of leiomyoma in the respiratory tract is infrequent, although various cases have been presented [1,2]. Respiratory tract leiomyomata have been classified into three groups -tracheal, bronchial and parenchymal -which differ in clinical manifestation and diagnostic approach 2.…”

Section: Introductionmentioning

confidence: 99%

Pedunculated Pulmonary Parenchymal Leiomyoma Associated with Hypertrophic Osteoarthropathy: Case Report

Politi¹,

Comin²,

Barale³

et al. 2014

TOCTSJ

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Hypertrophic osteoarthropathy, a condition of osteitis of the long bones that manifests clinically with clubbing, is often secondary to a thoracic neoplasm, especially lung carcinoma in long-time smokers. We report an unusual case in which hypertrophic osteoarthropathy was the only manifestation of a benign pulmonary parenchymal leiomyoma. A 38-year-old non-smoking man had bilateral clubbing of the fingers. Hypertrophic osteoarthropathy was diagnosed when radiography revealed thin lamellar deposits along the metatarsals and phalanges of the hands and similar osteal changes in the feet. Respiratory tests indicated normal lung functioning, but computed tomography revealed a 5x4 cm2 lobulated mass in the lower left lung which did not take up 18F-FDG on positron emission tomography. Exploratory thoracotomy revealed a pedunculated neoplasm which was removed by standard lobectomy. Histopathological diagnosis indicated the presence of smooth muscle spindle cells but absence of mitotic activity, nuclear atypia or necrosis, leading to a diagnosis of pulmonary parenchymal leiomyoma. Four months after surgery, the patient experienced a noticeable reduction in the finger clubbing. Hypertrophic osteoarthropathy may be the presenting characteristic of benign masses such as pulmonary leiomyoma.

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“…Among all tumors surgically excised from the lung, only 4% are benign and, of these, only 2% are leiomyomas, a benign form of smooth muscle tumor 3,15 .…”

Section: Discussionmentioning

confidence: 99%

Endobronchial leiomyoma: an unusual non-defining neoplasm in a patient with AIDS

Metta

Corti

Redini

et al. 2009

Rev. Inst. Med. trop. S. Paulo

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SUMMARYSmooth muscle neoplasms are more frequent in human immunodeficiency infected children than in HIV seropositive adults. Endobronchial leiomyoma is a rare benign tumor in HIV infected adult patients. Epstein-Barr virus (EBV) has been implicated in the pathogenesis of these tumors. Here we describe an adult patient with HIV infection with atelectasis of the left upper pulmonary lobe as the first clinical expression of an intrabronchial leiomyoma. In this case, we can not show the association with EBV. Our report suggests that smooth muscle tumors as leiomyoma should be included in the differential diagnosis of endobronchial masses in AIDS patients.

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Leiomyomas of the lower respiratory tract.

Cited by 106 publications

References 13 publications

Primary Leiomyoma of The Chest Wall

Primary Leiomyoma of The Chest Wall

Pedunculated Pulmonary Parenchymal Leiomyoma Associated with Hypertrophic Osteoarthropathy: Case Report

Endobronchial leiomyoma: an unusual non-defining neoplasm in a patient with AIDS

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