Leiomyomas of the duodenum

Sérraf, Alain; Klein, Ehud; Schneebaum, Shlomo; Davidson, Brian R; Herzic, E.; Ben-Ari, G

doi:10.1002/jso.2930390310

Cited by 8 publications

(3 citation statements)

References 12 publications

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“…Benign tumors of the upper gastrointestinal tract are uncommon, and only 25% to 30% of them are leiomyomas [1][2][3][4][5][6][7][8]. The distribution of leiomyomas in the gastrointestinal tract varies, with the stomach being the most common site of occurrence, followed by the jejunum and duodenum.…”

Section: Discussionmentioning

confidence: 99%

“…They occur relatively less frequently in the duodenum (5%) than in the stomach (61.5%) or jejunum (19%) [2]. Most of these lesions are small submucosal tumors that are usually asymptomatic and are most often discovered incidentally during endoscopy or at autopsy, although there have been case reports of duodenal leiomyomas causing significant upper gastrointestinal hemorrhage [3][4][5], pain [6], and intestinal obstruction [7,8]. The optimal management of symptomatic lesions is unknown.…”

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confidence: 99%

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Surgical Management of Duodenal Leiomyomas

et al. 2001

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Duodenal leiomyomas are rare neoplasms and when present are usually asymptomatic. There are, however, isolated case reports of such leiomyomas giving rise to complications including gastrointestinal hemorrhage and obstruction. The purpose of this study was to review the surgical experience with duodenal leiomyomas at a large tertiary referral center. A retrospective review was performed of all patients with histologically proven duodenal leiomyomas encountered from 1975 to 1995. Twelve patients with surgically treated duodenal leiomyomas were identified. There were eight men and four women with a mean age of 57 years (range 20-73 years) at diagnosis. Anemia was the presenting sign in 10 patients (83%). The mean hemoglobin level at presentation was 10.8 +/- 2.67 g/dl. Other presenting signs included melena (n = 5) and epigastric tenderness (n = 4). No patient had obstructive symptoms. Upper endoscopy visualized the lesion in 9 of 10 patients, but endoscopic biopsy provided an accurate histologic diagnosis in only two of six patients biopsied. All resected specimens underwent frozen section and permanent histopathologic analysis. Local excision was performed in eight patients, as benignancy was anticipated at surgical exploration and frozen section findings. Two patients underwent segmental duodenal resection with primary end-to-end anastomosis, and two patients underwent a Whipple procedure. There was no perioperative mortality. Morbidity was minimal. There was no tumor recurrence during a median follow-up of 8.4 years. Gastrointestinal blood loss is the most common complication of duodenal leiomyomas requiring surgical intervention. Small symptomatic leiomyomas with benign features may be safely treated with local excision.

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Surgical Management of Duodenal Leiomyomas

et al. 2001

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“…Of these, 198 (14 %) were located in the duodenum, and of these only 32 (2.1 %) were leiomyomas [109]. These polypoid lesions may be discovered incidentally or they may cause symptoms such as abdominal pain, gastrointestinal bleeding, and obstruction [110,111]. They present between the 6th and 7th decades of life, with a slight male predominance [111].…”

Section: Leiomyomasmentioning

confidence: 99%

Sporadic duodenal polyps: classification, investigation, and management

Culver¹,

As²

2011

Endoscopy

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Sporadic duodenal polyps are uncommon, being found in up to 5% of patients referred for upper gastrointestinal endoscopy. They are often discovered incidentally and are usually asymptomatic. The histological subtype of polyps cannot always be determined on endoscopic appearance alone, and biopsy is advocated. The need for further imaging, endoscopic procedures, surgical resection, and surveillance is determined by the histological features, neoplastic potential and associated symptoms. This review describes the different subtypes of sporadic duodenal polyp: adenomas, hamartomas, gastric metaplasia, inflammatory fibroids, lipomas, leiomyomas, carcinoids, stromal tumors, solitary Peutz-Jeghers polyps, lymphomas, and other rare benign and malignant lesions. It describes the epidemiology, clinical presentation, investigation, management options, and screening and surveillance strategies for each, based on current evidence.

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Duodenum: Basics of Radiologic-Pathologic Correlations

Lichtenstein¹,

Scholz²

Radiologic-Pathologic Correlations From Head to Toe

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Leiomyomas of the duodenum

Cited by 8 publications

References 12 publications

Surgical Management of Duodenal Leiomyomas

Surgical Management of Duodenal Leiomyomas

Sporadic duodenal polyps: classification, investigation, and management

Duodenum: Basics of Radiologic-Pathologic Correlations

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