Leiomiosarcoma de la vena renal izquierda

Colón-Rodríguez, A.; Bernardos-García, L. E.; Calleja-Kempin, J.; Reparaz, L.; Gimeno-Aranguez, M.; Martínez-Baena, Darío

doi:10.1016/s0003-3170(04)74851-8

Cited by 12 publications

(2 citation statements)

References 45 publications

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“…Histological biopsy before treatment was performed in 9 patients (13.4%; 9/67); 1 patient had biopsy during exploration 9 , 4 patients had CT guided CNB 19 , 20 , 27 , 50 , the biopsy type for 2 patients was not specified in the article 33 , 41 and 2 patients had biopsy through femoral approach during cavography. 36 , 43 FNAB before operation was performed in 1 patient 34 and in our case (3.0%; 22/67). The mean tumour size was 8.9 cm, described in 54 cases (80.6%; 54/67).…”

Section: Resultsmentioning

confidence: 50%

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Leiomyosarcoma of the renal vein: analysis of outcome and prognostic factors in the world case series of 67 patients

Novak

Perhavec

Maturen

et al. 2016

Radiology and Oncology

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BackgroundLeiomyosarcoma is a rare malignant mesenchymal tumour. Some cases of leiomyosarcoma of the renal vein (LRV) have been reported in the literature, but no analysis of data and search for prognostic factors have been done so far. The aim of this review was to describe the LRV, to analyse overall survival (OS), local recurrence free survival (LRFS) and distant metastases free survival (DMFS) in LRV world case series and to identify significant predictors of OS, LRFS and DMFS.MethodsCases from the literature based on PubMed search and a case from our institution were included.ResultsSixty-seven patients with a mean age of 56.6 years were identified; 76.1% were women. Mean tumour size was 8.9 cm; in 68.7% located on the left side. Tumour thrombus extended into the inferior vena cava lumen in 13.4%. All patients but one underwent surgery (98.5%). After a median follow up of 24 months, the OS was 79.5%. LRFS was 83.5% after a median follow up of 21.5 months and DMFS was 76.1% after a median follow up of 22 months. Factors predictive of OS in univariate analysis were surgical margins, while factors predictive of LRFS were inferior vena cava luminal extension and grade. No factors predictive of DMFS were identified. In multivariate analysis none of the factors were predictive of OS, LRFS and DMFS.ConclusionsBased on the literature review and presented case some conclusions can be made. LRV is usually located in the hilum of the kidney. It should be considered in differential diagnosis of renal and retroperitoneal masses, particularly in women over the age 40, on the left side and in the absence of haematuria. Core needle biopsy should be performed. Patients should be managed by sarcoma multidisciplinary team. LRV should be surgically removed, with negative margins.

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Section: Resultsmentioning

confidence: 50%

“… 36 Two patients were alive with disease and on palliative care at the time of report. 34 , 46 Three patients (4.5%; 3/67) had local recurrence, 10 patients (14.9%; 10/67) had local recurrence and dissemination and 20 patients (29.9%; 20/67) had dissemination of the disease after treatment. Spread was hematogenous to different organs.…”

Section: Resultsmentioning

confidence: 99%