2003
DOI: 10.1152/ajpendo.00273.2002
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Leg and arm lactate and substrate kinetics during exercise

Abstract: To study the role of muscle mass and muscle activity on lactate and energy kinetics during exercise, whole body and limb lactate, glucose, and fatty acid fluxes were determined in six elite cross-country skiers during roller-skiing for 40 min with the diagonal stride (Continuous Arm ϩ Leg) followed by 10 min of double poling and diagonal stride at 72-76% maximal O2 uptake. A high lactate appearance rate (Ra, 184 Ϯ 17 mol ⅐ kg Ϫ1 ⅐ min Ϫ1 ) but a low arterial lactate concentration (ϳ2.5 mmol/l) were observed du… Show more

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Cited by 152 publications
(152 citation statements)
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“…Thus, it seems that in the CM the extracellular lactate shuttle (cell to cell) via MCTs was determinant for the reduction of [La]. This hypothesis is corroborated by the study by van Hall et al 27 , who measured the lactate balance between upper and lower limbs during 40 minutes of continuous exercise in skiing, using both limbs, the data showed that the arms produced lactate, while the legs removed it.…”
Section: Discussionmentioning
confidence: 57%
“…Thus, it seems that in the CM the extracellular lactate shuttle (cell to cell) via MCTs was determinant for the reduction of [La]. This hypothesis is corroborated by the study by van Hall et al 27 , who measured the lactate balance between upper and lower limbs during 40 minutes of continuous exercise in skiing, using both limbs, the data showed that the arms produced lactate, while the legs removed it.…”
Section: Discussionmentioning
confidence: 57%
“…Animals process lactate at high rates even under resting, normoxic conditions, and in mammals, many studies have shown that inherently high baseline lactate fluxes are strongly stimulated during exercise (Bergman et al, 1999;Donovan and Brooks, 1983;Issekutz et al, 1976;Stanley et al, 1985;Van Hall et al, 2003;Weber et al, 1987). Little is known about lactate fluxes in fish because adequate methods to quantify these fluxes accurately under controlled exercise conditions have only recently become available.…”
Section: Introductionmentioning
confidence: 99%
“…Research has confirmed that O 2 -cost during arm work and whole body work is related to higher percentage of type-II-fibers in arm muscles 23,24 and that the amount of external work is greater. 19 Van Hall, et al 25 and Jensen-Urstad, et al 26 provided evidence that during whole body work more carbohydrates are utilized and more lactate is released than during leg. Moreover, extra oxygen is needed to overcome the forces of gravity.…”
Section: Discussionmentioning
confidence: 99%