Left ventricular systolic dysfunction after acute coronary syndromes: incidence; prognosis and risk predictors

António, Natália; Monteiro, Sílvia; Lourenço, Carolina; Teixeira, Rogério; Baptista, R.; Jorge, Elisabete; Gonçalves, Francisco; Monteiro, Pedro; Gonçalves, Lino; Providência, Luí­s A.

doi:10.1016/s1567-4215(08)60375-6

Cited by 2 publications

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“…STEMI patients had higher long-term mortality due to higher mortality of the acute event within six months 24. Similar to our finding, Antonio,et al conducted a study and concluded that ST-elevation myocardial infarction was significantly more frequent in patients with LV systolic dysfunction and those patients showed higher levels of myocardial markers of necrosis 11…”

Section: Discussionsupporting

confidence: 91%

“…This is expected as with aging process, the heart thickness, stiffness increase and significant functional deficit with stress occur which in turn result in decreasing cardiac reserve and function 10. Similar to our finding, a study concluded that age is independent predictor of LV systolic dysfunction after ACS which can be easily detectable on initial evaluation of the patient 11…”

Section: Discussionsupporting

confidence: 88%

“…Moreover, patients with diabetes were found to have worse left ventricular systolic dysfunction and a higher-risk coronary anatomy 13. Similarly, Antonio et al identified DM as a strong predictor of LV dysfunction which could predict poor outcome in patients with ACS 11. Also, diabetic patients showed comparable depression in LV longitudinal systolic indices when compared with age- and gender-matched healthy controls; the co-existence of diabetes leads to further impairment in LV longitudinal systolic function in an additive manner 14.…”

Section: Discussionmentioning

confidence: 98%

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Cardiovascular risk factors profile in patients with acute coronary syndrome with particular reference to left ventricular ejection fraction

Khaled

Matahen

2018

Indian Heart Journal

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We concluded that DM, presence of significant ischemic MR, and increased number, severity of diseased coronaries all were independent predictors of LV dysfunction (LVEF <40%) which is known to predict poor outcome. Identification of those risk predictors upon patient evaluation could be helpful to identify high risk-patients, in need of particular care, aggressive therapy and close follow-up to improve their poor outcome.

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Section: Discussionsupporting

confidence: 91%

Section: Discussionsupporting

confidence: 88%

Section: Discussionmentioning

confidence: 98%

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Cardiovascular risk factors profile in patients with acute coronary syndrome with particular reference to left ventricular ejection fraction

Khaled

Matahen

2018

Indian Heart Journal

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“…Killip class shows the degree of heart failure after AMI 24 . This score is helpful in terms of orientation treatment in the acute phase of AMI.…”

Section: Discussionmentioning

confidence: 99%

Akut anterior ST segment miyokard infarktüsü sonrası GRACE risk skorunun sol ventrikül ejeksiyon fraksiyonundaki prediktif değeri

Tosun

KORUCUK

Kılınç³

et al. 2019

Cukurova Medical Journal

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The aim of the study is to investigate the predictive value of GRACE score for left ventricular ejection fraction (LVEF) after acute anterior segment acute myocardial infarction (AMI). Despite rapid and complete reperfusion in AMI, inadequate recovery of left ventricular function may result in a decrease in LVEF. Materials and Methods: We retrospectively analyzed 712 patients presented with AMI and 290 patients were included. Patients were divided into two groups according to LVEF and a value <50% was defined as depressed EF group (group 1), a value ≥50% was defined as preserved EF group (group 2). The GRACE risk scores of all patients were calculated. Results: 132 patients were included in the group 1, 158 patients were included in the group 2. In-hospital death GRACE risk score and in-hospital death/MI GRACE risk score were higher in group 1. A significant negative correlation was found between risk scores and LVEF. In multivariate regression analysis, in-hospital death risk score, and in-hospital death/MI risk score were found to be independently predictors of depressed LVEF. Conclusion: GRACE risk score has a clinically important role predicting depressed LVEF in acute anterior segment AMI patients treated with primary PCI. Amaç: Çalışmanın amacı, akut anteriyor miyokard infarktüsünden (AMİ) sonra sol ventrikül ejeksiyon fraksiyonu (SVEF) için GRACE risk skorunun prediktif değerini araştırmaktır. AMİ' da hızlı ve tam reperfüzyona rağmen, sol ventrikül fonksiyonunun yetersiz iyileşmesi SVEF' de azalmaya neden olabilir. Gereç ve Yöntem: AMİ ile başvuran 712 hasta retrospektif olarak incelendi ve 290 hasta çalışmaya dahil edildi. Hastalar SVEF' ye göre iki gruba ayrıldı ve <% 50' den düşük bir değer düşük EF grubu (grup 1), ≥%50 değeri korunmuş EF grubu (grup 2) olarak tanımlandı. Tüm hastaların GRACE risk skorları hesaplandı. Bulgular: Grup 1' e 132, grup 2' ye 158 hasta dahil edildi. Hastane içi mortalite GRACE risk skoru ve hastane içi mortalite/Mİ GRACE risk skoru grup 1' de daha yüksek bulundu. Risk skorları ile SVEF arasında anlamlı bir negatif korelasyon mevcuttu. Çok değişkenli regresyon analizinde hastane içi mortalite riski skoru ve hastane içi mortalite/Mİ risk skoru düşük SVEF' nin bağımsız belirleyicileri olarak bulundu. Sonuç: GRACE risk skoru, primer perkütan coroner girişim ile tedavi edilen akut anteriyor AMİ hastalarında düşük SVEF' yi öngörmede klinik olarak önemli bir role sahiptir.

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Left ventricular systolic dysfunction after acute coronary syndromes: incidence; prognosis and risk predictors

Cited by 2 publications

References 0 publications

Cardiovascular risk factors profile in patients with acute coronary syndrome with particular reference to left ventricular ejection fraction

Cardiovascular risk factors profile in patients with acute coronary syndrome with particular reference to left ventricular ejection fraction

Akut anterior ST segment miyokard infarktüsü sonrası GRACE risk skorunun sol ventrikül ejeksiyon fraksiyonundaki prediktif değeri

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