Left ventricular responses to upright isometric handgrip and deadlift in men with coronary artery disease

Sagiv, Michael; Hanson, Peter; Besozzi, Myrwood C.; Nagle, F. J.

doi:10.1016/0002-9149(85)90492-8

Cited by 56 publications

(30 citation statements)

References 10 publications

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“…However, cal culations of the mean arterial blood pressures did not reveal significant differences between groups. This pressure response is in agree ment with previous studies [5,12]. For the normal groups and the older weight lifters, the similar increase in blood pressure during exer cise may be because they were performing contractions at similar absolute force exerted.…”

Section: Discussionsupporting

confidence: 91%

“…Physiological responses differ, depending upon whether they result from a pressure overload and increased pe ripheral vascular resistance or from a volume overload [3], It has been shown that hearts of normal subjects engaged predominantly in pressure overload activities, such as weight lifting exercise, develop a concentric left ven tricular hypertrophy [4], Static muscle activity occurs in day-to-day tasks. It has been assumed that this type of activity is potentially dangerous for the older population, due to a seemingly inappropriate blood pressure response [5]. This has the effect of placing a large load on the left ventri cle which might have significant effects on the systolic function.…”

Section: Introductionmentioning

confidence: 99%

“…The increase in blood pres sure during static dead-lift exercise ( fig. 1) has been shown to be exaggerated in older persons [5], Under such conditions, hypertrophy of the left ventricle may be associated with left ventricular systolic function abnormalities and depressed contractility [6,7], However, the effects of hypertrophy on myocardial per formance are still controversial. In instances of successful adaptation to the pressure over load, as found in young weight lifters [8], hypertrophy per se does not always produce intrinsic depression of the myocardial ino tropic state [9.…”

Section: Introductionmentioning

confidence: 99%

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Effects of Chronic Overload Training and Aging on Left Ventricular Systolic Function

Sagiv

Sagiv²,

Ben‐Sira³

et al. 1997

Gerontology

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To examine the effects of age and chronic overload training on left ventricular systolic function during static exercise, Doppler echocardiography studies were performed in 14 young (28 ± 6 years) and 10 older (51 ± 3 years) weight lifters and also in 14 young (29 ± 6 years) and 10 older (52 ± 1.1 years) normal individuals during upright dead-lift isometric exercise, at 30% of maximal voluntary contraction for 3 min. At rest, older weight lifters demonstrated impaired left ventricular systolic function as compared with the other three groups. During exercise, peak and mean velocity values increased significantly (p < 0.05) from resting values in the young groups, but remained unchanged in the older groups. Flow period and acceleration and deceleration times were significantly (p < 0.05) lower in the younger subjects than those observed for the old ones, with the highest (p < 0.05) values obtained by the old weight lifters. This study suggests that the differences between the groups are related to differences in impedance and not to fundamental changes in the properties of the myocardium.

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Section: Discussionsupporting

confidence: 91%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Effects of Chronic Overload Training and Aging on Left Ventricular Systolic Function

Sagiv

Sagiv²,

Ben‐Sira³

et al. 1997

Gerontology

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“…In normal subjects, endurance exercise results in an increase in systolic blood pressure despite a decrease in total peripheral resistance. This increase has been shown to be due to an increase in cardiac output caused by increases in heart rate and stroke volume due to a greater left ventricular end-diastolic volume on the one hand and a decrease in left ventricular end-systolic volume on the other (Sagiv et al 1985(Sagiv et al , 1986. In the present study, 7 men and 7 women underwent a O 2max test reaching cardiac output values of 24.3 l á min )1 for the men and 22.4 l á min )1 for the women.…”

Section: Discussionmentioning

confidence: 99%

The effect of gender on left ventricular function immediately after the wingate test

Ben‐Sira

Sagiv

1997

European Journal of Applied Physiology

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The effect of gender on left ventricular systolic function and exercise haemodynamics in healthy young subjects was studied during 30-s all-out sudden strenuous dynamic exercise. A group of 22 men [19.3 (SD 1) years] 20 women [19.1 (SD 1) years] volunteered to participate in this study. Two-dimensional direct M-mode and Doppler echocardiograph studies were performed with the subject in the sitting position. The Doppler examination of flow was located with continuous-wave, interrogating ascending aorta measurements. The subjects completed the study without showing any electrocardiograph abnormalities. An interaction effect with stroke volume (P < 0.05) was characterized by a decrease in the men and an increase of stroke volume in the women. Cardiac output rose significantly (P < 0.05) up to 14.5 (SD 6) 1.min-1) for the men and 12.1 (SD 4) 1.min-1 for the women compared to the rest values [5.8 (SD 0.4) and 4.7 (SD 0.5) 1.min-1, respectively]. Flow velocity integral and acceleration time differed significantly between the two groups at rest (P < 0.05). During exercise these differences showed an interaction effect (P < 0.05). These results would indicate that normal men and women respond to sudden strenuous exercise by reducing their left ventricular systolic function, with a significantly greater decrease in women (P < 0.05). The gender differences in the haemodynamic responses during the present study, may, as suggested by others, be attributable to differences in energy metabolism. In addition, changes in Doppler parameters of aortic flow, haemodynamics and blood pressure responses during sudden strenuous exercise differed markedly from those seen before with endurance exercise.

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“…In addition to the isometric stress imposed during isodynamic exercise, other potential factors contribute to this variability, including speed and grade [2]. Because isometric maneuvers can be very demanding, due to the pressor response [4], it increases the afterload during isodynamic exercise which may affect the left ventricular global performance [5]. Therefore, the elderly have traditionally been advised to avoid activities that require isometric muscle contraction due to the pressor response.…”

Section: Introductionmentioning

confidence: 99%

Effect of Changes in Load Carriage while Walking on the Left Ventricular Function in Highly Trained Elderly Subjects

et al. 2002

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Background: In previous studies, the effect of isometric stress on the dynamic performance of a graded exercise test in normal subjects augmented afterload and brought about changes in left ventricular function more often than did results from physical exercise. Objective: This study used the metabolic charts and echocardiography to examine the influence of two different types of load carriage during 30 min of treadmill walking on left ventricular function, hemodynamics, and cardiovascular responses. Methods: Fifteen elderly (age 66.1 ± 3.5 years) aerobically well-trained male subjects (VO_{2 peak} 44.2 ± 5.0 ml·kg^–1·min^–1) volunteered in this study. The subjects walked on a treadmill (at a speed of 4.5 km·h^–1), carrying a load of 20 kg during one session and a load of 30 kg during a second session. Results: Following the 30-min exercise in each session, significant (p < 0.05) differences were noted between the 20-kg and the 30-kg work loads with regard to cardiac output (6.8 ± 0.5 and 7.8 ± 0.4 l·min^–1), heart rate (114.0 ± 11.0 and 126.0 ± 10.0 beats·min^–1), diastolic blood pressure (79.4 ± 5.0 and 84.3 ± 5.0 mm Hg, mean arterial blood pressure (104.0 ± 4.0 and 109.2 ± 3.0 mm Hg), and left ventricular contractility ratio (3.3 ± 0.4 and 3.6 ± 0.3). No significant differences were noted between the work loads with regard to systolic blood pressure, cardiac output, left ventricular volumes, and ejection fraction. Conclusions: This study suggests that in the highly trained elderly, the influence of the autoregulation mechanism dominates during combined dynamic and isometric exercises, thus the opposing force to the left ventricular ejection is reduced which in turn does not change left ventricular global function.

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Left ventricular responses to upright isometric handgrip and deadlift in men with coronary artery disease

Cited by 56 publications

References 10 publications

Effects of Chronic Overload Training and Aging on Left Ventricular Systolic Function

Effects of Chronic Overload Training and Aging on Left Ventricular Systolic Function

The effect of gender on left ventricular function immediately after the wingate test

Effect of Changes in Load Carriage while Walking on the Left Ventricular Function in Highly Trained Elderly Subjects

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