Left Ventricular Non-Compaction: Review of the Current Diagnostic Challenges and Consequences in Athletes

Femia, Giuseppe; Semsarian, Christopher; Ross, Samantha Barratt; Celermajer, David S.; Puranik, Rajesh

doi:10.3390/medicina56120697

Cited by 8 publications

(6 citation statements)

References 42 publications

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“…Complications ranging from heart failure to sudden death due to arrhythmias, and thromboembolic events have been documented in this disease [17]. Our patient quickly benefited from a curative treatment for her AVRNT with a regular 24-hour Holter ECG follow-up.…”

Section: Discussionmentioning

confidence: 76%

A Young Healthy Woman with Supraventricular Tachycardia Reveals an Underlying Left Ventricular Non-compaction Cardiomyopathy: A Rare Case Report

Tahir

Mulendelé²,

Foudail³

et al. 2023

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LVNC (left ventricular non-compaction) is a rare congenital cardiomyopathy with a reported incidence of 0.05% in adults. It can occur in isolation or affect both ventricles. It’s characterized by prominent LV trabeculae and deep intertrabecular recesses which are filled with blood from the ventricular cavity without evidence of communication to the epicardial coronary artery system. Frequent premature supra ventricular tachycardia as unique finding in LVNC cardiomyopathy is rare manifestation of this disease. We report a case of a frequent persistent supraventricular tachycardia as first manifestation of a patient with LVNC cardiomyopathy in a young healthy woman who despite radio frequency ablation therapy of the supraventricular tachycardia remains symptomatic. The patient was later placed on medical therapy based on a non-cardio selective beta-blocker with a good clinical outcome without recurrent of supra-ventricular arrythmias.

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Section: Discussionmentioning

confidence: 76%

A Young Healthy Woman with Supraventricular Tachycardia Reveals an Underlying Left Ventricular Non-compaction Cardiomyopathy: A Rare Case Report

Tahir

Mulendelé²,

Foudail³

et al. 2023

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“…The accuracy of the echocardiographic diagnostic criteria is still under debate. The Chin criteria showed the highest diagnosis rate (79%), compared to the Jenni criteria (64%) and the Stollberger and Finsterer criteria (53%) [10]. Moreover, the correlation between the criteria is weak-only 30% of patients diagnosed with LVNC meet all three criteria [10].…”

Section: Discussionmentioning

confidence: 94%

“…The Chin criteria showed the highest diagnosis rate (79%), compared to the Jenni criteria (64%) and the Stollberger and Finsterer criteria (53%) [10]. Moreover, the correlation between the criteria is weak-only 30% of patients diagnosed with LVNC meet all three criteria [10]. 3D echocardiography can improve the diagnosis, but there are still many limits to echocardiography in detecting LVNC.…”

Section: Discussionmentioning

confidence: 98%

Left Ventricular Non-compaction Cardiomyopathy and Polycystic Kidney Disease Revealed by Inappropriate Polycythemia: A Fortuitous Association? Case Report

Hodorogea

Gheorghe

Pârvu

et al. 2022

Romanian Journal of Cardiology

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We present the case of a patient with heart failure with reduced left ventricular (LV) ejection fraction, diagnosed in the first instance by echocardiography and further on by more accurate cardiac magnetic resonance imaging with LV non-compaction (LVNC). Blood tests showed high erythrocyte and hematocrit levels, inappropriate in this setting, whilst Janus Kinase 2V617F mutation was absent, erythropoietin level was slightly increased, and arterial O2 pressure level was normal. At the time of diagnosis, the patient had mild renal impairment, and abdominal echography revealed bilateral polycystic kidney disease (PKD). The patient had one son who fulfilled the echocardiographic criteria for LVNC and had bilateral renal cysts revealed by abdominal ultrasound. The genes responsible for autosomal dominant PKD (ADPKD) development are PKD1, on chromosome 16, coding for polycystin 1 and PKD2, on chromosome 4, coding for polycystin 2. There are some experimental data which suggest that polycystins might play an important role in cardiac development and hence PKD1 and PKD2 mutations may be involved in primary cardiomyopathies. These data could explain this particular association between LVNC and ADPKD. To date, there are only a few isolated cases reported, and only one shows this association in more than one member of the same family. Further genetic testing in the few reported cases would presumably elucidate whether this finding is the result of complex genetic synergy or just a simple coincidence.

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“…Esto se ha visto en los deportistas de alto rendimiento: los sujetos entrenados presentan significativamente más trabeculaciones que los no entrenados (18,3% vs. 7%) como lo han publicado es sus respectivos trabajos Fermia y Gati. (8,9) 2. La segunda parte de la definición de enfermedad de la OMS expresa "…por causas en general conocidas…".…”

Section: Distribución Del Mncunclassified

Miocardio no compacto ¿Puede no ser una enfermedad? Razonamiento crítico sobre 140 miocardios no compactos evaluados con resonancia magnética cardiovascular

Obregón

Cayre

2022

Rev Argen Cardiol

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Para que una alteración física sea considerada una enfermedad, debe cumplir con los criterios definidos por la OMS. El miocardio no compacto (MNC) es una hipertrabeculación ventricular no bien definida, de la que se duda si es una miocardiopatíaen sí misma, o solo una variación de la normalidad. Nosotros analizamos 161 resonancias magnéticas cardíacas realizadasa 140 pacientes con MNC y sus relaciones con otras patologías, exponiéndolos a los criterios de “enfermedad” definidos porla OMS. Tras un análisis crítico, consideramos que no debería ser considerada una miocardiopatía en sí misma, sino unaadaptación miocárdica ante condiciones adversas.

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Left Ventricular Non-Compaction: Review of the Current Diagnostic Challenges and Consequences in Athletes

Cited by 8 publications

References 42 publications

A Young Healthy Woman with Supraventricular Tachycardia Reveals an Underlying Left Ventricular Non-compaction Cardiomyopathy: A Rare Case Report

A Young Healthy Woman with Supraventricular Tachycardia Reveals an Underlying Left Ventricular Non-compaction Cardiomyopathy: A Rare Case Report

Left Ventricular Non-compaction Cardiomyopathy and Polycystic Kidney Disease Revealed by Inappropriate Polycythemia: A Fortuitous Association? Case Report

Miocardio no compacto ¿Puede no ser una enfermedad? Razonamiento crítico sobre 140 miocardios no compactos evaluados con resonancia magnética cardiovascular

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