Left ventricular non-compaction cardiomyopathy and ischaemic stroke

Bistriceanu, Cătălina Elena; Danciu, Florentina Anca; Cuciureanu, Dan Iulian

doi:10.5603/pjnns.a2022.0079

Cited by 1 publication

(2 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Moreover, the prefrontal and temporal white-matter networks in the motor-task state were divided into two networks in the motor state, which implied spatial reorganization in the task-related network in the motor condition. Frontotemporal regions are involved in the majority of patients with generalized epilepsy, 52,53 which might lead to a fixed and over-integrated network architecture in epilepsy.…”

Section: Discussionmentioning

confidence: 99%

“…Moreover, the prefrontal and temporal white‐matter networks in the motor‐task state were divided into two networks in the motor state, which implied spatial reorganization in the task‐related network in the motor condition. Frontotemporal regions are involved in the majority of patients with generalized epilepsy, 52,53 which might lead to a fixed and over‐integrated network architecture in epilepsy. Here, we found that patients failed to flexibly change the network reorganization across resting and motor states, which might be related to the hyper‐integration of brain networks caused by disease 54 .…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Brain activation and connection across resting and motor‐task states in patients with generalized tonic–clonic seizures

Jiang,

Wang,

Pei

et al. 2024

CNS Neurosci Ther

View full text Add to dashboard Cite

AimsMotor abnormalities have been identified as one common symptom in patients with generalized tonic–clonic seizures (GTCS) inspiring us to explore the disease in a motor execution condition, which might provide novel insight into the pathomechanism.MethodsResting‐state and motor‐task fMRI data were collected from 50 patients with GTCS, including 18 patients newly diagnosed without antiepileptic drugs (ND_GTCS) and 32 patients receiving antiepileptic drugs (AEDs_GTCS). Motor activation and its association with head motion and cerebral gradients were assessed. Whole‐brain network connectivity across resting and motor states was further calculated and compared between groups.ResultsAll patients showed over‐activation in the postcentral gyrus and the ND_GTCS showed decreased activation in putamen. Specifically, activation maps of ND_GTCS showed an abnormal correlation with head motion and cerebral gradient. Moreover, we detected altered functional network connectivity in patients within states and across resting and motor states by using repeated‐measures analysis of variance. Patients did not show abnormal connectivity in the resting state, while distributed abnormal connectivity in the motor‐task state. Decreased across‐state network connectivity was also found in all patients.ConclusionConvergent findings suggested the over‐response of activation and connection of the brain to motor execution in GTCS, providing new clues to uncover motor susceptibility underlying the disease.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%