Left ventricular function in patients with chronic obstructive pulmonary disease

Ventricular Geometry, Strain, and Rotational Mechanics in Pulmonary Hypertension

“…The right and left ventricles share the interventricular septum (IVS) and are contained within the pericardial sac, inducing interdependence in ventricular structure and function1,2. Chronic right ventricular (RV) pressure overload leads to a leftward shift and flattening of the IVS1-4.…”

“…Chronic right ventricular (RV) pressure overload leads to a leftward shift and flattening of the IVS1-4. The degree of severity of chronic RV pressure overload has traditionally relied on the degree of pulmonary artery systolic pressure (PASP) rise, yet patients may present with a wide range of disease severity within a similar range of elevated PASP.…”

Clinical and phonocardiographic evaluation of left ventricular function in patients with chronic obstructive pulmonary disease

“…[14][15][16][17][18][19] Postmortem reports have revealed the presence of left ventricular hypertrophy in a significant percentage of patients with COPD. [14][15][20][21][22] The measurement of LV function was difficult and complicated until the advent of non-invasive techniques.…”

Left Ventricular Performance and Dimensions in Patients with Severe Emphysema

“…Load-dependent indices of LV function have been used in previous studies to evaluate LV function in patients with emphysema. Two studies showed no abnormality of LV function (5,6), while one study (7) demonstrated abnormal LV function curves in the majority of patients with chronic obstructive lung disease. Others have suggested that LV systolic dysfunction, assessed by LV area ejection fraction (AEF), is unusual in patients with severe parenchymal lung disease without pulmonary hypertension (4,8,9), but LV area ejection fraction may be decreased in patients with emphysema and pulmonary hypertension because of ventricular interaction (10).…”