Left Ventricular Function in Hypertension: New Insight by Speckle Tracking Echocardiography

Imbalzano, Egidio; Zito, Concetta; Carerj, Scipione; Oreto, Giuseppe; Mandraffino, Giuseppe; Cusmà-Piccione, Maurizio; Bella, Gianluca Di; Saitta, Carlo; Saitta, Antonino

doi:10.1111/j.1540-8175.2011.01410.x

Cited by 133 publications

(121 citation statements)

References 53 publications

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“…Therefore, we deduced there were more remarkable myocardial damages in EP. Notably, GLS in hypertension is reported as the first to be impaired in subclinical LV damage and GCS in hypertensive heart disease is recognized as compensatory mechanism acting to prevent a failure of systolic function in the presence of a subendocardial damage with longitudinal function impairment [22]. However, in our study, there was no significant change in GLS and the value of GCS was higher in LP vs. EP.…”

Section: Discussionmentioning

confidence: 42%

Maternal cardiac remodeling and dysfunction in preeclampsia: a three-dimensional speckle-tracking echocardiography study

Cong

Fan

Yang

et al. 2015

Int J Cardiovasc Imaging

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Aims preeclampsia (PE) is a pregnancy complication that remains a main cause of maternal morbidity and mortality. The aims of this study were to investigate left ventricle (LV) performance in PE and to compare maternal cardiac function between early-onset preeclampsia (EP) and late-onset preeclampsia (LP) by novel threedimensional (3D) speckle-tracking echocardiography (STE) parameters while considering LV loading and shape. Methods and Results Two-dimensional echocardiography and 3D STE were performed in 43 women with EP, 41 women with LP, and 81 normal pregnancies. Global longitudinal strain (GLS), global circumferential strain (GCS), global area strain (GAS), and global radial strain (GRS) were measured using 3D speckle-tracking software. There was eccentric hypertrophy and reduced LV ejection fraction (EF) in PE; meanwhile, GLS in EP and LP, GCS in LP, as well as GAS and GRS in EP significantly decreased in PE versus controls. All 3D strain indices were correlated with gestation age. Increased left atrial (LA) volume index was detected in PE. Higher LV mass index and lower 3D-derived strain value were present in women with EP compared to that in women with LP. Conclusion PE cases exhibited significant eccentric hypertrophy, ventricular dysfunction, and LA remodeling. Furthermore, myocardial deformation abnormalities preceded chamber dysfunction in this hypertensive disorder complicated pregnancy. Compared with LP, women with EP demonstrated more remarkable cardiac damage.

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Section: Discussionmentioning

confidence: 42%

Maternal cardiac remodeling and dysfunction in preeclampsia: a three-dimensional speckle-tracking echocardiography study

Cong

Fan

Yang

et al. 2015

Int J Cardiovasc Imaging

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“…47 Similar alterations in LV GLS with preservation of radial and circumferential deformation have been described in systemic hypertension, indicating that an abnormal pattern of LV deformation results from afterload-induced myocardial hypertrophy. 51 Normal ranges for CMR-FT indices in the pediatric age group considering age, sex, and allometry have become recently available. 52 More studies correlating CMR-FT indices with clinical outcomes are needed in pediatric and adult CHD imaging.…”

Section: Applications In Chdmentioning

confidence: 99%

Cardiovascular Magnetic Resonance Myocardial Feature Tracking

Schuster

Hor

Kowallick

et al. 2016

Circ: Cardiovascular Imaging

307

206

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Abstract-Heart failure-induced cardiovascular morbidity and mortality constitute a major health problem worldwide and result from diverse pathogeneses, including coronary artery disease, nonischemic cardiomyopathies, and arrhythmias. Assessment of cardiovascular performance is important for early diagnosis and accurate management of patients at risk of heart failure. During the past decade, cardiovascular magnetic resonance myocardial feature tracking has emerged as a useful tool for the quantitative evaluation of cardiovascular function. The method allows quantification of biatrial and biventricular mechanics from measures of deformation: strain, torsion, and dyssynchrony. The purpose of this article is to review the basic principles, clinical applications, accuracy, and reproducibility of cardiovascular magnetic resonance myocardial feature tracking, highlighting the prognostic implications. It will also provide an outlook on how this field might evolve in the future. (Circ Cardiovasc Imaging. 2016;9:e004077.

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“…Newer echocardiography methods such as speckle tracking echocardiography (STE) allow robust assessment of the longitudinal shortening that is predominantly influenced by subendocardial fibres and is more suited to detect subtle myocardial damage. 9 Recently, Adda et al 10 reported markedly reduced LV longitudinal shortening in patients with PLF: a finding that may help explain the underlying pathophysiological mechanisms. In the application of STE analysis to the left atrium, three separate components 11 can be characterized: reservoir function, conduit function, and active LA contraction ( Figure 1).…”

Section: Introductionmentioning

confidence: 99%

Recovery of left ventricular and left atrial mechanics in various entities of aortic stenosis 12 months after TAVI

Spethmann

Baldenhofer

Dreger

et al. 2013

European Heart Journal - Cardiovascular Imaging

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BackgroundTranscatheter aortic valve implantation (TAVI) has been shown to improve prognosis of high-risk patients. Data, however, concerning the impact of TAVI on regional and global left atrial (LA) and left ventricular (LV) mechanics in varying entities of severe aortic stenosis (AS) are sparse, particularly in patients with paradoxical low-flow (PLF) AS or with reduced LV ejection fraction (LVEF). This study evaluated the effects of TAVI on LA and LV mechanics in varying entities of AS 12 months after implantation. Methods and resultsA total of 54 consecutive patients with severe AS (24 with a normal LVEF and normal flow, 16 with PLF, and 14 with a reduced LVEF) were included. Speckle tracking echocardiography was performed before and 12 months after TAVI to determine LV global and regional longitudinal deformation as well as LA function (reservoir function, conduit phase, and active contraction). In all the three entities of AS, there was a significant improvement in global and regional LV longitudinal function (average global longitudinal strain: 214.1 + 3.9% at baseline vs. 216.5 + 4.0% after TAVI, P , 0.001). Interestingly, the beneficial effects were most pronounced in patients with PLF (214.0 + 2.9 vs. 217.0 + 4.4%, P , 0.031). Moreover, the atrial reservoir and conduit function recovered significantly after TAVI in all patients. ConclusionIn conclusion, regardless of the underlying AS entity, TAVI improves global and regional LV and LA mechanics within 12 months.--

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Left Ventricular Function in Hypertension: New Insight by Speckle Tracking Echocardiography

Cited by 133 publications

References 53 publications

Maternal cardiac remodeling and dysfunction in preeclampsia: a three-dimensional speckle-tracking echocardiography study

Maternal cardiac remodeling and dysfunction in preeclampsia: a three-dimensional speckle-tracking echocardiography study

Cardiovascular Magnetic Resonance Myocardial Feature Tracking

Recovery of left ventricular and left atrial mechanics in various entities of aortic stenosis 12 months after TAVI

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