Left ventricular function, cardiac dysrhythmias, atrial activation, and volumes in nondipper hypertensive individuals with left ventricular hypertrophy

Cardiac ectopy in chronic autonomic failure

“…Non-dipping also characterizes patients with orthostatic hypotension [2]. Hypertensives with evidence of left ventricular hypertrophy have a high frequency of PACs [20], and CAF patients have been reported to have an increased frequency of echocardiographic left ventricular hypertrophy [19]; however, in the present study most NOH patients had normal interventricular septal thickness. The frequency of PACs increases with normal aging [1,15,21].…”

The influence of circadian blood pressure changes on aortic distensibility and left ventricular diastolic function in hypertensive individuals

“…However, the association between non-dipper and target-organ damage is still a controversy. Some studies have concluded that the lack of nocturnal decrease in BP is not associated with an increase in left ventricular mass or in arterial disease independently of age [39][40][41]. Contrary to these suggestions, other studies have shown that target organ damage is more pronounced in hypertensive patients with the lack of nocturnal fall in BP [9,32,36].…”

Effects of dipper and non-dipper status of essential hypertension on left atrial mechanical functions

“…LA function have been evaluated in hypertensive patients [16,19,21,24,26] but the effects of dipper and non-dipper status of essential hypertension on left atrial mechanical functions in hypertensive patients are unknown. We believed that our study is the first to examine the effect of dipper and non-dipper status of essential hypertension on left atrial mechanical function systematically.…”

“…Left ventricular diastolic filling is impaired in hypertensive heart disease state. Blood flow from left atrium towards left ventricle is deteriorated due to increase in left ventricular stiffness [19]. In chronic process with hypertensive patients left ventricular diastolic dysfunction and left ventricular compliance appears to be reduced.…”

“…Increase of left ventricular diastolic pressure in the early stage of the heart failure decreases early passive filling by diminishing maximal diastolic left atrioventricular pressure gradient, on the other hand, late filling increases. It was ascertained in Framingham study that the increased systolic blood pressure and pulse pressure were closely related to enlarged LA dimensions [19,20]. The high BP measurements observed in the nighttime recordings of ambulatory blood pressure monitorizations are indetermined variable of the LA dilatation [22 -24].…”