Left ventricular contraction patterns in Takotsubo Syndrome and their correlation with long-term clinical outcome

Anemia: Another Stone in the Wall of Takotsubo Outcomes?

“…10 On the other hand, recent evidence showed that patients with TS had also a poor long-term prognosis, with an overall mortality of 39% within 4 years. 11 Once again, in multivariate analysis, anemia was a strong predictor for long-term mortality (OR: 3.93, 95% CI: 1.02-2.08, P = .015). 11 These results open up the question on whether correction, and which kind of correction, of anemia and ID may be useful and safe.…”

Long-term outcomes in patients with Takotsubo syndrome

“…In their study, myocardial injury in the acute phase was worse in the patients with typical contraction pattern than those with atypical contraction pattern [1] . In addition to the outcome comparison that the authors did, a comparison of echocardiographic cardiac function would be of great interest.…”

“…Long-term clinical outcome in patients with Takotsubo syndrome remains uncertain. Gaede and colleagues demonstrated that a 4-year mortality in patients with Takotsubo syndrome was approximately 40%, nearly half of the surviving patients showed persistent symptoms, and its recurrence rate was approximately 10% [1] .…”

“…The authors found that anemia, which was defined by hemoglobin values <12 g/dL for women and <14 g/dL for men according to the WHO criteria, was independently associated with the long-term mortality [1] . Anemia would have a considerable association with Takotsubo syndrome not only as a marker of severe background as the authors speculated but also as a cause of worse clinical outcomes as often discussed in the literature of heart failure [2] .…”

“…Approximately 10% of the patients experienced the recurrence of Takotsubo syndrome [1] . Such a cohort would be a specific group to whom we should pay special attention during the follow-up period.…”