Addi"ional informa"ion is available a" "he end of "he chap"er h""p://dx.doi.org/10.5772/53396. Introduction "cute myocardial infarction "MI , despite advances in health care delivery systems, education, and primary prevention still remains a significant problem. Fortunately, with these advances and early interventions, there has been a decline in the incidence of mechanical complications. Unfortunately, while becoming less common, when mechanical complications occur and despite advances and evolving techniques in the surgical management of these problems, morbidity and mortality remain high. Post-myocardial infarction ventricular septal rupture PI-VSD has challenged and intrigued clinicians for years. The timing of presentation can be quite variable, as they tend to occur in patients several days after their initial cardiovascular insult acute PI-VSD -and unfortunately, they can occur in patients who appear to otherwise be doing well. In addition, while less common, some patients might not present until weeks, if not longer, after their "MI with symptoms prompting a work-up that might reveal a chronic PI-VSD. Early PI-VSDs tend to be catastrophic and can result in death. The pathology is also variable and complex, but common themes include . acute right ventricular RV failure from a sudden increase in pressure, volume, and flow from left to right shunts,. pulmonary hypertension also from the acute increase in RV work and flow and . worsening cardiac output, often with manifestations of shock and end-organ damage, from acute left ventricular LV dysfunction and left-right shunting.Definitive management remains surgical, however, controversies continue to exist regarding the timing of surgery, the role of concomitant coronary revascularization, and the evolving © 2013 Firs"enberg e" al.; licensee InTech. This is an open access ar"icle dis"rib""ed "nder "he "erms of "he Crea"ive Commons A""rib""ion License (h""p://crea"ivecommons.org/licenses/by/3.0), which permi"s "nres"ric"ed "se, dis"rib""ion, and reprod"c"ion in any medi"m, provided "he original work is properly ci"ed.role of percutaneous closure devices. Unfortunately, despite early repair and improvement in techniques and peri-operative management, the short and long-term outcomes remain less than ideal.
. HistoryPost-myocardial infarction ventricular septal defects PI-VSD were described first at autopsy [ ]. It was not until that the pre-mortem pathophysiology was understood [ ]. [ ], described the association with coronary artery disease and acute myocardial infarction [ ].The first report of a surgical repair came in when Denton Cooley described a patient weeks after the initial diagnosis who underwent operative intervention [ ]. With advances in the peri-operative and intra-operative management of the cardiovascular surgery patients there were reports of survival in what was previously felt to be an inherently fatal problem. Most of the successful operative cases occurred in patients who presented in congestive heart failure weeks after their initial acute...