Left Ventricular Aneurysm of Uncertain Etiology with Recurrent Ventricular Arrhythmias

Maloy, William C.; Arrants, Jack E.; B, Sowell; Hendrix, Grady H.

doi:10.1056/nejm197109162851205

Cited by 51 publications

(15 citation statements)

References 13 publications

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“…Spontaneous rupture of a diverticulum has been found in some patients with sudden death 12 , 17 . Recurrent and refractory tachycardiac arrhythmias, including ventricular tachycardia or ventricular fibrillation, may be another mechanism contributing to sudden death 18–20 . Systemic embolism, 21 congestive heart failure, 18 and severe valvular regurgitation 22 were also reported.…”

Section: Discussionmentioning

confidence: 99%

Asymptomatic Isolated Congenital Left Ventricular Muscular Diverticulum In An Adult: A Case Report

et al. 2003

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Congenital ventricular diverticulum is a very rare malformation in adults. We describe a 21-year-old male with a congenital muscular left ventricular diverticulum in the inferior wall. The lesion was suspected on two-dimensional transthoracic echocardiography; transesophageal echocardiography allowed clear detection of the diverticulum as well of mild mitral valve prolapse. The diagnosis was confirmed by cardiac catheterization. There were no other thoracoabdominal or cardiac anomalies, the patient was asymptomatic, and surgery was not deemed necessary.

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Section: Discussionmentioning

confidence: 99%

Asymptomatic Isolated Congenital Left Ventricular Muscular Diverticulum In An Adult: A Case Report

et al. 2003

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“…The initial case reported by Maloy et al was a 26-year-old woman with an apical congenital left ventricular aneurysm who had recurrent ventricular tachycardia. 9 Later, Fellow et al reported 2 patients with aborted sudden cardiac death and 1 patient who presented with syncope and documented nonsustained ventricular tachycardia. 15 Shen et al described a male patient with a sustained ventricular tachycardia caused by a posterobasal left ventricular diverticulum, which was inducible during electrophysiologic testing.…”

Section: Discussionmentioning

confidence: 99%

“…8 There are only few observational case reports and small series on congenital left ventricular aneurysms and diverticula in the medical literature. [9][10][11][12][13][14] The association of this abnormality with ventricular tachyarrhythmia was reported in 1971 by Maloy et al 9 However, very little is known on the clinical outcome of these patients to date. In this study, we aimed to investigate the long-term outcome of patients with congenital left ventricular aneurysms and diverticula who had ventricular arrhythmias or presyncope/syncope at initial presentation.…”

mentioning

confidence: 99%

Incidence and Prognosis of Ventricular Arrhythmias in Patients with Congenital Left Ventricular Aneurysms or Diverticula

Haegeli

Ercin

Steffel

et al. 2015

The American Journal of Medicine

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The clinical outcome of patients with congenital left ventricular aneurysms and diverticula and arrhythmia is variable. Clinical ventricular tachycardia in these patients is often monomorphic and usually inducible during electrophysiologic study, indicating a role for this test in risk stratification. Appropriate discharges are frequent in implantable cardioverter defibrillator recipients with congenital left ventricular aneurysms and diverticula.

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“…The initial case reported by Maloy et al involved a 26-year-old woman with an apical LVA who had recurrent ventricular tachycardias. 33 Later, Fellows et al reported a small patient series: 2 patients with aborted sudden cardiac death and 1 patient who presented with syncope and documented non-sustained ventricular tachycardias. 22 Shen et al described a male patient with sustained ventricular tachycardia caused by a postero-basal LVD, which was also inducible during electrophysiological testing.…”

Section: Discussionmentioning

confidence: 99%

Long-Term Prognosis of Adult Patients With Isolated Congenital Left Ventricular Aneurysm or Diverticulum and Abnormal Electrocardiogram Patterns

Ohlow

Lauer

Lotze

et al. 2012

Circ J

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Circulation Journal Official Journal of the Japanese Circulation Society http://www. j-circ.or.jp ongenital left ventricular aneurysm (LVA) and diverticulum (LVD) are rare malformations and approximately 500 cases have been published in the literature since the first description in 1816. 1 A recent study found a prevalence of 0.76% in adult patients undergoing coronary angiography. 2 Although most investigators distinguish between LVA and LVD, the cause, histopathology, and clinical implications remain controversial. 3-7 The advent of echocardiography and magnetic resonance imaging has led to earlier diagnosis, including prenatal detection. 8-10 The published research on these anomalies consists, beside 1 large single center study, 2 of case reports and small case series, mostly on infants and young children with large aneurysms and poor clinical outcome. 10-16 High morbidity and mortality rates due to heart failure, aneurysm rupture, thromboembolism, and sudden death of unclear cause have been reported. 3,4 More recent published data demonstrated a more favorable course with no cardiac mortality in adults with congenital LVA and LVD. 2,8 A significant proportion of the published literature report arrhythmias in patients with these anomalies. 2,3,17-25 Recently, our own group was able to demonstrate that patients with congenital LVA/ LVD had a high incidence of distinctly abnormal electrocardiograms (ECGs) compared to an age-and gender-matched control group. 26 The purpose of the present study was to evaluate the prognosis and risk factors of patients with a diagnosis of isolated congenital LVA or LVD, having ECG abnormalities. Methods DefinitionThe diagnosis of congenital LVA or LVD was established after angiographic exclusion of coronary artery disease. Clinical and ECG local or systemic inflammation, traumatic causes and car- Background: Congenital left ventricular aneurysm (LVA) and diverticulum (LVD) are rare cardiac anomalies frequently associated with electrocardiogram (ECG) abnormalities. The aim of this study was to evaluate the long-term prognosis in such patients.

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Left Ventricular Aneurysm of Uncertain Etiology with Recurrent Ventricular Arrhythmias

Cited by 51 publications

References 13 publications

Asymptomatic Isolated Congenital Left Ventricular Muscular Diverticulum In An Adult: A Case Report

Asymptomatic Isolated Congenital Left Ventricular Muscular Diverticulum In An Adult: A Case Report

Incidence and Prognosis of Ventricular Arrhythmias in Patients with Congenital Left Ventricular Aneurysms or Diverticula

Long-Term Prognosis of Adult Patients With Isolated Congenital Left Ventricular Aneurysm or Diverticulum and Abnormal Electrocardiogram Patterns

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