Left ventricle non-compaction cardiomyopathy: Different clinical scenarios and magnetic resonance imaging findings

Abstract

Left ventricle non-compaction cardiomyopathy is currently considered as a well-defined individual entity. However, it includes a broad spectrum of clinical, radiological and pathophysiological findings. In this review we describe 3 different scenarios of this entity: an isolated case with severe left ventricle dysfunction, an "associated" case in a patient with previous atrial septum defect and pulmonary stenosis and finally, as a finding in a patient with a transient cerebrovascular ischemic attack. In the 2 last cases, both asymptomatic, morphological criteria of left ventricle non-compaction were found but, ventricular function was normal and cardiac-MRI showed no late gadolinium hyperenhancement. Periodical follow-up and familial screening were recommended. Natural history and prognosis factors of this disease are still not well known. Further and longer series of patients with this diagnosis are needed to completely define radiological criteria, clinical presentation and evolution.

Estimation of Prevalence of the Left Ventricular Noncompaction Among Adults

“…Short of this, echocardiographic yield of LVNC from a large academic center can provide a rough estimate of the prevalence of this disease. Available reports on the prevalence of LVNC come from different geographic regions such as Europe, Asia and North America with no such data from Latin America(23). In a large pediatric series, LVNC is reported to be the most common form of unclassified cardiomyopathies(6,7).…”