Left Thyroid Lobe Hemiagenesis with Hyperthyroidism: Report of a Case

Kocakuşak, Ahmet; Akıncı, Muzaffer; Arıkan, Soykan; Sunar, Haldun; Yücel, Ahmet Fikret; Şentürk, Orçun

doi:10.1007/s00595-003-2726-9

Cited by 17 publications

(17 citation statements)

References 13 publications

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“…Most common of these being hyperthyroidism, associated with thyroid hemiagenesis. However, as seen in our patient, hemithyroid agenesis can also be associated with a hypothyroid or euthyroid states as well [3,4,6]. A recent large cohort case study revealed that patients with thyroid hemiagenesis were more likely to develop thyroid pathology in the remnant thyroid lobe, including functional, morphological, and autoimmune diseases with Hashimoto's thyroiditis being the most common of the pathologies encountered [7].…”

Section: Discussionsupporting

confidence: 56%

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Thyroid Hemiagenesis: A Rare Finding

Rohith¹,

Sood²

2015

JCR

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Abstract:Thyroid hemiagenesis is a rare embryological condition characterized by absence of one of the lobes of the thyroid gland, with the left lobe being absent in 80% of cases and right lobe absent in 20% of cases (a left to right hemi-agenesis ratio of 4:1). We report a case of 25 year old female who presented with right neck mass gradually increasing in size over a period of 2 months. Patient had the history of weight loss and fatigability. The patient work up included an ultrasound neck followed by plain CT neck and contrast CT neck. Ultrasound neck showed absence of left lobe and part of isthmus of the thyroid gland with the right lobe showing features of thyroiditis. These findings were supported by plain and contrast CT neck findings.

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Section: Discussionsupporting

confidence: 56%

“…Hemithyroid agenesis is a rare congenital anomaly of the thyroid and been has found to be three time more common in females as compared to males [4]. In 80% cases the left thyroid lobe is absent and in about 50% of patients with left hemithyroid agenesis will also have an absent thyroid isthmus [5].…”

Section: Discussionmentioning

confidence: 99%

Thyroid Hemiagenesis: A Rare Finding

Rohith¹,

Sood²

2015

JCR

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“…In fact, many cases of hemiagenesis discovered upon workup of the hyperthyroidism. However as noted earlier and in our patient, hemithyroid agenesis can be associated with a hypothyroid or euthyroid state as well [2,4,6]. A recent large cohort case study revealed that patients with thyroid hemiagenesis were more likely to develop thyroid pathology.…”

Section: Discussionmentioning

confidence: 55%

“…Hemithyroid agenesis a rare congenital anomaly of thyroid has found to be three time more common in females as compared to males [4]. In 80% the left thyroid lobe is absent and in about 50% of patients with left hemithyroid agenesis will also have an absent thyroid isthmus [5].…”

Section: Discussionmentioning

confidence: 99%

Thyroid Hemiagenesis: Report of a Case and Review of Literature

Peña

Robertson

Walvekar

2011

Indian J Otolaryngol Head Neck Surg

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Our objective was to report an incidental finding of thyroid hemiagenesis in a patient who presented with a left neck mass, present a review of literature, and to discuss management of this diagnosis. Case report and review of literature. An internet-based literature search was performed via Pubmed with key words, "hemithyroid agenesis, thyroid hemiagenesis, absent thyroid gland". Clinical, pathological, radiologic data and follow up information is reported. A 55 year old woman with a left neck mass presented to our service. A diagnostic CT scan of the head and neck revealed an unrelated finding of an absent left thyroid lobe. A review of the CT imaging did not reveal ectopic thyroid tissue. A complete physical examination including a flexible laryngoscopy was unremarkable. The neck mass was pathologically a granulomatous lesion on surgical pathology. Thyroid function tests were within normal limits. In follow-up, patient remains asymptomatic. Hemithyroid agenesis is most commonly associated with hyperthyroidism, although, hypothyroidism has been reported. Pathology that can be associated in the remnant thyroid lobe includes adenocarcinoma, adenoma, multinodular goiter, and chronic thyroiditis. In counseling patients, it is important to educate them regarding these associated conditions and offer appropriate work up if indicated. Incidental thyroid agenesis with a negative work up can then be observed.

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“…The prevalence is higher in women (3:1, as was also in the present case), which may indicate a possible gender association (2). Hyperthyroidism has been reported to be the most common clinical presentation leading to an incidental diagnosis of the hemiagenesis (11–13). Our case presented with multi-nodular goiter which has be reported as the second most common association.…”

Section: Discussionmentioning

confidence: 99%

Congenital thyroid hemiagenesis with multinodular goiter

Bhartiya

Verma

Basu

et al. 2014

Acta Radiologica Short Reports

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Thyroid hemiagenesis is a rare form of thyroid dysgenesis characterized by an absence of half of the thyroid gland. Developmental hemi-thyroid anomalies can result from either an abnormal descent or an agenesis of one lobe of the thyroid gland. We report a case of a 40-year-old woman with history of a longstanding gradually progressive thyroid swelling without any complication. An ultrasonographic examination diagnosed the absence of the left thyroid lobe and enlargement of the right lobe, which was confirmed on a computed tomography (CT) angiogram and a radionuclide scan of the neck. A cytological examination showed nodular goiter with cystic degeneration. Right subtotal thyroidectomy was performed and histopathological examination confirmed adenomatous goiter with degenerative changes. We report the rarity of the condition and emphasize the role of a comprehensive radiological, cytological, and radionuclide algorithm for an accurate preoperative diagnosis and subsequent management.

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Left Thyroid Lobe Hemiagenesis with Hyperthyroidism: Report of a Case

Cited by 17 publications

References 13 publications

Thyroid Hemiagenesis: A Rare Finding

Thyroid Hemiagenesis: A Rare Finding

Thyroid Hemiagenesis: Report of a Case and Review of Literature

Congenital thyroid hemiagenesis with multinodular goiter

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