Left Pulmonary Artery Coarctation Associated with Pneumonia and Pulmonary Hypertension in a Cat

Valente, Carlotta; Tursi, Massimiliano; Poser, Helen; Guglielmini, Carlo

doi:10.3390/vetsci8120325

Cited by 2 publications

(5 citation statements)

References 31 publications

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“…13,67,83–85 In the case reported by Baron Toaldo et al, 13 the cat received a single dose of carboplatin prior to developing PTE and PH; in this case, it is not known if the PH developed as a result of the chemotherapeutic agent or the PTE. In the case reported by Valente et al, 67 the cat presented with interstitial pneumonia, as well as coarctation of the pulmonary artery, with severe thrombosis and mid-intimal hypertrophy. Other cases reported include a 14-year-old male neutered, feline leukemia virus-positive cat with PH and cor pulmonale secondary to thromboembolism after repeated surgical debridement of an abscess, 84 and a 10-year-old male Siamese with HCM.…”

Section: Classification Of Phmentioning

confidence: 98%

“…Several case reports have documented PH in cats with PTE, although some of these include patients with more than one disease process, which could have resulted in PH. 13,67,83–85 In the case reported by Baron Toaldo et al, 13 the cat received a single dose of carboplatin prior to developing PTE and PH; in this case, it is not known if the PH developed as a result of the chemotherapeutic agent or the PTE. In the case reported by Valente et al, 67 the cat presented with interstitial pneumonia, as well as coarctation of the pulmonary artery, with severe thrombosis and mid-intimal hypertrophy.…”

Section: Classification Of Phmentioning

confidence: 98%

“…There have also been recent reports of cats with infectious pneumonia demonstrating PH; one case was described in the presentation by Escalda et al, 54 and another was described in a cat with left pulmonary artery coarctation and interstitial pneumonia. 67 Toxin-induced acute lung injury and PH has been reported in the cat. There are numerous experimental studies in which cats are used as a model for PH.…”

Section: Ph Secondary To Respiratory Disease or Hypoxiamentioning

confidence: 99%

“…However, several of the cases documented above do, in fact, have two or more potential pathologies and could therefore be classified as type 6 PH. 13,67,83 It is important to recognize that in some cases there can be multiple disease processes occurring, and that, where possible, the overall management plan should address all of the underlying disorders.…”

Section: Parasitic Diseasementioning

confidence: 99%

Section: Classification Of Phmentioning

confidence: 99%

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Feline pulmonary hypertension: are we overlooking an important comorbidity?

Rolph

Cavanaugh

2022

Journal of Feline Medicine and Surgery

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Pulmonary hypertension (PH) is a potential complication in many disease states, yet it has been largely overlooked in feline medicine. Recently, increased awareness of potential underlying causes has led to a wider understanding of the disease process in humans, with a focus on tailoring therapy to include specific treatment of the underlying etiology. Most of these treatments are not yet available in veterinary medicine, but as they move from the human to the veterinary field, it would be beneficial to better understand the forms of PH encountered in different species. Recently, diagnosis and classification of PH in dogs has been the focus of an American College of Veterinary Internal Medicine consensus statement, yet this condition has received little attention in cats. It is therefore our intention to raise awareness of this condition in cats and to propose a classification system for the types of PH seen in feline patients. As new medications are developed for the treatment of PH, it is important to recognize which forms of PH are seen in feline patients and understand the etiology of the disease. There are many reports of PH (or suspected PH based on echocardiographic assessment) in cats. In this review, we highlight the large number of conditions, and different etiologies, that are associated with PH. Improving understanding of this condition will bring us closer to being able to investigate the benefits of potential new diagnostics and therapies as they become available.

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Section: Classification Of Phmentioning

confidence: 98%

Section: Classification Of Phmentioning

confidence: 98%

Section: Ph Secondary To Respiratory Disease or Hypoxiamentioning

confidence: 99%

Section: Parasitic Diseasementioning

confidence: 99%

Section: Classification Of Phmentioning

confidence: 99%

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Feline pulmonary hypertension: are we overlooking an important comorbidity?

Rolph

Cavanaugh

2022

Journal of Feline Medicine and Surgery

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A Retrospective Study of Sildenafil Administration in 55 Cats with Cardiopulmonary Disease (2009–2021)

Huynh,

Dolan,

Karlin

et al. 2024

Animals

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Sildenafil is a drug used to successfully manage a variety of cardiopulmonary disorders in people and dogs, but there is limited information on its use in cats. The objective was to review the medical records of cats that received sildenafil as part of their clinical management. Medical records and pharmacy databases were searched for cats that received sildenafil for ≥24 h between 2009 and 2021, and data were collected from medical records. Fifty-five cats received sildenafil for ≥24 h and were included in the study: 43 with primary cardiac disease (acquired, n = 28; congenital, n = 15) and 12 with primary respiratory disease. Side effects possibly attributed to sildenafil were identified in two cats (systemic hypotension, n = 1; polydipsia, n = 1), and sildenafil was discontinued in the cat with hypotension. Sildenafil was discontinued in an additional three cats due to a lack of improvement in clinical signs. No cat was documented to develop worsening pulmonary edema within 72 h of starting sildenafil. Median duration of sildenafil administration was 87 days (range, 2–2362 days). Sildenafil administration in cats appeared to be generally well-tolerated. Studies are needed to determine whether sildenafil administration to cats with cardiopulmonary disease improves the quality of life or survival times.

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Left Pulmonary Artery Coarctation Associated with Pneumonia and Pulmonary Hypertension in a Cat

Cited by 2 publications

References 31 publications

Feline pulmonary hypertension: are we overlooking an important comorbidity?

Feline pulmonary hypertension: are we overlooking an important comorbidity?

A Retrospective Study of Sildenafil Administration in 55 Cats with Cardiopulmonary Disease (2009–2021)

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