he transfemoral and the transradial approach are the standard access routes for coronary angiography and percutaneous coronary interventions. A transapical left ventricular access is sometimes used for diagnostic purposes and has been described for structural cardiac interventions, but not for coronary artery interventions. 1-4 A significant number of patients who undergo catheter-based aortic valve implantation also require coronary intervention. In selected cases, it may be desirable to perform coronary revascularization via the transapical access, for example if aortic disease makes a transfemoral or transradial approach impossible or may lead to complications. We report a case of successful transapical coronary intervention in a patient undergoing transapical catheter-based aortic valve implantation.
CaseA 92-year-old male patient with severe symptomatic aortic stenosis (valve area, 0.4 cm 2 ; peak pressure gradient, 87 mm Hg; mean pressure gradient, 47 mm Hg), diabetes, renal failure (epidermal growth factor receptor, 28 mL/min per 1.73 m 2 ), obstructive pulmonary disease, and EURO score of 13 (predicted operative risk, 49%), was scheduled for catheter-based aortic valve implantation. Invasive coronary angiography via the transfemoral approach was complicated by dissection of the iliac artery and revealed a high-grade stenosis (80%) of the mid left anterior descending coronary artery (LAD). Due to extensive periphareal vascular disease, the transapical approach was chosen for aortic valve implantation. Because of the prior complication via the transfemoral route and lack of sufficiently palpable radial pulses, a single-stage procedure combining coronary intervention and valve implantation via the left transapical approach was considered. First, a left anterolateral minimal thoracotomy was performed. Two purse string sutures were placed into the left ventricular apex and lateral to the LAD. The ventricle was punctured and a 14-French sheath was placed. A guide wire was advanced via the aortic valve and a 6F multiaccess catheter-3 guiding catheter passed through the aortic valve to intubate the left coronary ostium. No hemodynamic consequences were observed after passing the catheter through the aortic valve. Two coronary guide wires (Runthrough, Terumo and Galeo F, Biotronik) were placed into the LAD as backup support. Subsequently, the LAD stenosis was treated by direct placement of a drug eluting stent (Integrity Resolute 3.5/15; Figure A-D). After removal of the coronary guide wires and catheter, aortic valve implantation (EdwardsSapien, 23 mm) was performed successfully and without any complications via the 14-French sheath already in place. The patient was discharged from the hospital 10 days after the procedure in good general condition.
DiscussionTo our knowledge, we report the first coronary artery intervention via a transapical approach. Since the 1950s, transapical procedures using left ventricular apical puncture have mainly been performed to provide hemodynamic data in the presence of mechanical...