Left Gastric Artery Embolization in Obese, Prediabetic Patients: A Pilot Study

Embolização da artéria gástrica esquerda como alternativa para supressão de apetite e perda de peso em pacientes obesos: uma revisão integrativa

“…Ainda no mesmo ano, Zaitoun et al (2019) publicou um estudo piloto incluiu 10 pacientes, sendo 7 mulheres e 3 homens, todos obesos e pré-diabéticos com idade média de 37,5 ± 8,8 anos e IMC >30kg / m², internados para perda de peso entre janeiro de 2017 e junho de 2018. O estudo visava avaliar o impacto do LGAE nesses pacientes, os quais foram analisados HbA1c e o IMC antes do procedimento e 6 meses após, apresentando evidências promissoras quanto a redução clínica do HbA1c e do peso (Gunn & Weiss, 2019;Zaitoun et al, 2019).…”

Bariatric Arterial Embolization: Position Statement by the Pan Arab Interventional Radiology and the Saudi Interventional Radiology Societies

“…[26] Zaitoun et al reported significant BMI reduction of 8.8% at 6 months following the procedure. [27] Elens et al evaluated BAE in overweight patients with mean baseline BMI of 28.9 kg/m 2 . The mean early weight loss in 9 patients at 6 months was 8 kg, which corresponded to 10% of their baseline weight.…”

“…The HgbA1c-lowering effect of BAE is demonstrated in few reports. [8,10,27] Zaitoun et al evaluated the effect of BAE on 10 obese prediabetic patients with baseline BMI of 37.4 kg/m 2 and mean HgbA1c of 6. There was statistically significant reduction in mean BMI and HbA1c of 8.8% and 21.4%, respectively.…”

“…Larger particles may aggregate in the proximal vessel and may result in less devascularization of the target cells due to collateral filling from other arterial anastomosis. On the other hand, smaller particles may lead to more gastric ulcers but associated with greater weight loss as demonstrated in animal study by Fu et al [19] In the clinical studies on BAE, particulate size was 300-500 µ [8][9][10]26,27,30,31] or 500-700 µ. [4,28] Only single case of gastric perforation is reported with the use of 500-700 µ PVA particles, without details on the embolization procedure.…”

“…LGAE was performed in all previously reported studies. [4,[8][9][10][26][27][28]30,31] The gastroepiploic artery was embolized in 3 patients in the BEAT study. [9] • We recommend careful evaluation and mapping of the fundal arterial supply before bariatric embolization (Grade 1A).…”