Left atrium function and deformation in very preterm infants with and without volume load

Waal, Koert de; Phad, Nilkant; Boyle, Andrew

doi:10.1111/echo.14140

Cited by 14 publications

(20 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The median of the reported mean or median birth weight was 1,028 (range 797–1,259) g. The exact gestational ages and birth weights were not available for four studies ( 28 , 29 , 69 , 74 ). Seven of the 20 studies performed multiple cardiac ultrasounds to evaluate the PDA ( 21 , 24 , 25 , 27 , 67 , 72 , 73 ). The echocardiography was performed between 5 h and 28 days of postnatal age in all studies.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Spontaneous Closure of the Ductus Arteriosus in Preterm Infants: A Systematic Review

et al. 2020

View full text Add to dashboard Cite

The optimal management strategy for patent ductus arteriosus in preterm infants remains a topic of debate. Available evidence for a treatment strategy might be biased by the delayed spontaneous closure of the ductus arteriosus in preterm infants, which appears to depend on patient characteristics. We performed a systematic review of all literature on PDA studies to collect patient characteristics and reported numbers of patients with a ductus arteriosus and spontaneous closure. Spontaneous closure rates showed a high variability but were lowest in studies that only included preterm infants with gestational ages below 28 weeks or birth weights below 1,000 g (34% on day 4; 41% on day 7) compared to studies that also included infants with higher gestational ages or higher birth weights (up to 55% on day 3 and 78% on day 7). The probability of spontaneous closure of the ductus arteriosus keeps increasing until at least 1 week after birth which favors delayed treatment of only those infants that do not show spontaneous closure. Better prediction of the spontaneous closure of the ductus arteriosus in the individual newborn is a key factor to find the optimal management strategy for PDA in preterm infants.

show abstract

Section: Resultsmentioning

confidence: 99%

“…Twenty articles were included in group 2 (GA < 30 weeks and/or BW < 1,250 g) (11,(21)(22)(23)(24)(25)(26)(27)(28)(29)(67)(68)(69)(70)(71)(72)(73)(74)(75)(76). The median of the reported mean or median GA of the 2,980 patients in group 2 was 28.0 (range 26.2-28.8).…”

Section: Subgroup Analysismentioning

confidence: 99%

Spontaneous Closure of the Ductus Arteriosus in Preterm Infants: A Systematic Review

et al. 2020

View full text Add to dashboard Cite

show abstract

“…A recent consensus document tried to standardize definitions and techniques for using LAS in adults. The same would be needed in neonates, given the fact that the current available data were obtained with different types of software and different modalities of both image acquisition and postprocessing analysis [ 8 , 9 , 10 , 30 ].…”

Section: Discussionmentioning

confidence: 99%

“…To the best of our knowledge, few data on LAS are available in neonates and no data are available in the first days of life, also known as ‘transitional period’, when the transition from intrauterine to extrauterine circulation occurs [ 9 , 10 ].…”

Section: Introductionmentioning

confidence: 99%

Feasibility, Reproducibility and Reference Ranges of Left Atrial Strain in Preterm and Term Neonates in the First 48 h of Life

et al. 2022

View full text Add to dashboard Cite

Left atrial strain (LAS) is the most promising technique for assessment of diastolic dysfunction but few data are available in neonates. Our aim was to assess feasibility and reproducibility, and to provide reference ranges of LAS in healthy neonates in the first 48 h of life. We performed one echocardiography in 30 neonates to assess feasibility and develop a standard protocol for image acquisition and analysis. LAS reservoir (LASr), conduit (LAScd) and contraction (LASct) were measured. We performed echocardiography at 24 and 48 h of life in an unrelated cohort of 90 neonates. Median (range) gestational age and weight of the first cohort were 34.4 (26.4–40.2) weeks and 2075 (660–3680) g. LAS feasibility was 96.7%. Mean (SD) gestational age and weight of the second cohort were 34.2 (3.8) weeks and 2162 (833) g. Mean (SD) LASr significantly increased from 24 to 48 h: 32.9 (3.2) to 36.8 (4.6). Mean (SD) LAScd and LASct were stable: −20.6 (8.0) and −20.8 (9.9), −11.6 (4.9) and −13.5 (6.4). Intra and interobserver intraclass correlation coefficient for LASr, LAScd and LASct were 0.992, 0.993, 0.986 and 0.936, 0.938 and 0.871, respectively. We showed high feasibility and reproducibility of LAS in neonates and provided reference ranges.

show abstract

“…There have been conflicting reports between LA function indices determined by strain imaging with 2D-STE in humans. A previous study enrolling infants with patent ductus arteriosus demonstrated that cardiac volume overload secondary to this disease was associated with the impairment of reservoir and booster pump functions evaluated with LA strains and SRs [4]. On the contrary, another previous study including healthy humans showed that the acute decrease in cardiac volume load caused by a tilt maneuver was associated with the impairment of reservoir, conduit, and booster pump functions assessed on the basis of LA strains [10].…”

Section: Discussionmentioning

confidence: 99%

Effect of acute volume loading on left atrial strain values derived from two-dimensional speckle tracking echocardiography in dogs

Dermlim

Osuga

Nakamura

et al. 2019

The Journal of Veterinary Medical Science

View full text Add to dashboard Cite

The purpose of this study was to evaluate the cardiac acute volume loading effect on left atrial (LA) strain and strain rate (SR) parameters derived from two-dimensional speckle tracking echocardiography (2D-STE) in healthy dogs. Six healthy beagles were anesthetized and subjected to increase cardiac preload by intravenous infusion with lactated Ringer solution at 150 m l /kg/hr for 90 min. A Swan-Ganz catheter was placed to directly measure the mean pulmonary capillary wedge pressure (PCWP). Echocardiography was performed before (baseline) and at 15, 30, 45, 60, 75, and 90 min after acute volume loading began. Apical 4-chamber images focused on the LA were digitally recorded for later strain and SR analysis via 2D-STE. Acute volume loading significantly increased from baseline during LA strain and SR as assessed by the speckle tracking–based technique during reservoir and conduit function at 15 to 90 min after volume load began, and strain indices representing booster pump function were enhanced at 45 to 90 min. In addition, acute volume loading resulted in a significantly greater PCWP after fluid infusion. On multiple regression analysis, quadratic regression analysis was a better fit for the relationship between PCWP and all LA functional indices. Our findings indicated that LA function analyzed by strain and SR was enhanced during cardiac acute volume loading in healthy dogs. The change in strain and SR during acute volume loading should be interpreted with caution during the diagnosis of heart diseases related to volume overload.

show abstract

Left atrium function and deformation in very preterm infants with and without volume load

Abstract: LA 2DSTE analysis is feasible in preterm infants and provides detailed information on atrium mechanics. Further studies are needed to explore the clinical value of these new parameters in this population.

Cited by 14 publications

References 32 publications

Spontaneous Closure of the Ductus Arteriosus in Preterm Infants: A Systematic Review

Spontaneous Closure of the Ductus Arteriosus in Preterm Infants: A Systematic Review

Feasibility, Reproducibility and Reference Ranges of Left Atrial Strain in Preterm and Term Neonates in the First 48 h of Life

Effect of acute volume loading on left atrial strain values derived from two-dimensional speckle tracking echocardiography in dogs

Contact Info

Product

Resources

About