Left atrial volume determination by biplane two-dimensional echocardiography: Validation by cine computed tomography

Kircher, Barbara; Abbott, Joseph A.; Pau, Stanley; Gould, Robert G.; Himelman, Ronald B.; Higgins, Charles B.; Lipton, Martin J.; Schiller, Nelson B.

doi:10.1016/0002-8703(91)90200-2

Cited by 217 publications

(136 citation statements)

References 10 publications

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“…12 Left atrial volume was derived with the multiple-disks method. 13 LVH was assessed according to previously published criteria. 12,14 First, the wall thickness of each of the following myocardial segments was measured at both the mitral valve and the papillary muscle levels in the short-axis view 14 : anterior septum, anterior lateral, inferior lateral, and inferior septum.…”

Section: Echocardiographic Analysismentioning

confidence: 99%

Regression of Left Ventricular Hypertrophy After Nonsurgical Septal Reduction Therapy for Hypertrophic Obstructive Cardiomyopathy

et al. 2001

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Background-Hypertrophic obstructive cardiomyopathy (HOCM) is characterized by left ventricular hypertrophy (LVH) in the absence of increased external load. Recently, nonsurgical septal reduction therapy (NSRT) with intracoronary ethanol has been introduced to treat severely symptomatic patients with outflow tract obstruction. Its long-term effects on LV mass, however, are unknown. Methods and Results-The LV size, function, and outflow tract gradient of 26 HOCM patients (53Ϯ15 years old) who underwent NSRT were assessed by echocardiography at baseline and 1 and 2 years after the procedure. LVH was evaluated by wall thickness of individual myocardial segments, planimetered myocardial area, and mass. The outflow gradient decreased from 36Ϯ6 mm Hg before NSRT to 0Ϯ3 mm Hg at 2 years (PϽ0.001), with patients experiencing symptomatic improvement (PϽ0.05). LV end-diastolic and end-systolic dimensions increased significantly at both 1 and 2 years (PϽ0.001). All parameters of LVH showed evidence of regression. LV mass decreased (301Ϯ78 g at baseline, 223Ϯ5 g at 1 year, and 190Ϯ58 g at 2 years; PϽ0.01), with the 2-year reduction in mass related to infarct size and the acute reduction in outflow tract gradient (rϭ0.48, PϽ0.05 and rϭ0.63, PϽ0.01, respectively). Conclusions-NSRT results in LV remodeling that is characterized by an increase in LV size and a decrease in the extent of LVH.

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Section: Echocardiographic Analysismentioning

confidence: 99%

Regression of Left Ventricular Hypertrophy After Nonsurgical Septal Reduction Therapy for Hypertrophic Obstructive Cardiomyopathy

et al. 2001

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“…Historically, computed tomography (CT) and magnetic resonance imaging (MRI) have served as gold standards for left atrial volume, and 2 dimensional echocardiography (2D-TTE) was validated against these reference standards [10][11] . Echocardiography is currently the most common modality used to measure the left atrium because of its lower cost, portability and universal availability.…”

Section: Introductionmentioning

confidence: 99%

Left Atrial Volume: Comparison of 2D and 3D Transthoracic Echocardiography with ECG-gated CT Angiography

et al. 2012

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“…That would have provided a better identification of similarities, correlations or differences between techniques, as previously documented in people (Kircher et al 1991, Jenkins et al 2005. Therefore, it is clear that further studies are necessary in this area.…”

Section: Discussionmentioning

confidence: 85%

Determination of left atrial volume in healthy dogs and dogs with myxomatous mitral valve disease

et al. 2016

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RESUMO.-[Determinação do volume atrial esquerdo em cães sadios e portadores da degeneração mixomatosa da válvula mitral.] A mensuração do volume atrial esquerdo (VAE) pode ser obtido pelo método biplanar de Simpson via ecocardiografia. Embora na medicina tal parâmetro venha sendo considerado um marcador prognóstico da sobrecarga atrial esquerda em várias cardiopatias, nos cães com degeneração mixomatosa da válvula mitral (DMVM), valvulopatia caracterizada pela sobrecarga do átrio esquerdo (AE), a avaliação da sobrecarga atrial é realizada rotineiramente apelas pela relação entre o diâmetro do AE e da artéria Aorta (Ao) (AE:Ao). Portanto, procurou-se mensurar os valores do LAV indexados à área de superfície corporal (ASC) em cães sadios e em portadores da DMVM utilizando--se do método biplanar de Simpson. The left atrial volume (LAV) can be obtained using the biplane Simpson's method via echocardiography. Although in medicine this parameter has been considered to be a prognostic marker of left atrial enlargement in several cardiac diseases, in dogs with myxomatous mitral valve degeneration (MMVD), a valvulopathy characterized by left atrial (LA) volume overload, atrial enlargement is usually assessed by the LA-to-Aorta ratio (LA:Ao). Therefore, the body surface area (BSA)-indexed LAV was measured in healthy dogs and in dogs with MMVD using the biplane Simpson's method. For this purpose, a total of 107 healthy dogs (control) and 81 dogs with MMVD in ACVIM stages B1, B2 and C were assessed, with LAV being calculated during atrial diastole (d) and systole (s) through the biplane Simpson's method. Two-dimensional apical four-chamber (4C) and two-chamber (2C) images were obtained in every dog through the left parasternal window. The values obtained from healthy dogs were correlated with body weight using Pearson's test. An analysis of variance (ANOVA) and Tukey's test were used to compare healthy and MMVD dogs, as well as to investigate differences according with MMVD stages. A strong positive correlation was documented between either LAVd (r> 0.77) or LAVs (r> 0.73) and body weight in healthy dogs. The BSA-indexed LAV calculated for MMVD dogs was significantly different (p<0.01) from that obtained for the control group. Also, LAV was significantly different (P<0.05) when stages B2 and C, and B1 and C were compared. In conclusion, this study provided a reference for left atrial volume and the applicability of this technique to assess atrial overload in dogs with varying-stage MMVD.

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Left atrial volume determination by biplane two-dimensional echocardiography: Validation by cine computed tomography

Cited by 217 publications

References 10 publications

Regression of Left Ventricular Hypertrophy After Nonsurgical Septal Reduction Therapy for Hypertrophic Obstructive Cardiomyopathy

Regression of Left Ventricular Hypertrophy After Nonsurgical Septal Reduction Therapy for Hypertrophic Obstructive Cardiomyopathy

Left Atrial Volume: Comparison of 2D and 3D Transthoracic Echocardiography with ECG-gated CT Angiography

Determination of left atrial volume in healthy dogs and dogs with myxomatous mitral valve disease

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