Left atrial volume and the risk of paroxysmal atrial fibrillation in patients with hypertrophic cardiomyopathy

Tani, Tohru; Tanabe, Kazuaki; Ono, Miwa; Yamaguchi, Kazuto; Okada, Midori; Sumida, Toshiaki; Konda, Toshiko; Fujii, Yoko; Kawai, Junichi; Yagi, Toshikazu; Sato, Masatake; Ibuki, Motoaki; Katayama, Minako; Tamita, Koichi; Yamabe, Kenji; Yamamuro, Atsushi; Nagai, Kazuyuki; Shiratori, Kenichi; Morioka, Shigefumi

doi:10.1016/j.echo.2004.02.010

Cited by 126 publications

(98 citation statements)

References 17 publications

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“…The LAV is known to be a predictor of AF in patients with HCM [22]. In our study, both PWD and inter-atrial dyssynchrony were correlated with all phasic LAVs.…”

Section: Relationships Of Pwd and Atrial Emd To La Phasic Volumessupporting

confidence: 54%

Relationships between P wave dispersion, atrial electromechanical delay, left atrial remodeling, and NT-proBNP levels, in patients with hypertrophic cardiomyopathy

et al. 2015

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Background: We evaluated the associations among the well-known atrial fibrillation (AF) predictors including P-wave dispersion (PWD), intra-and inter-atrial electromechanical dyssynchrony (EMD), left atrial (LA) phasic functions, and plasma N-terminal prohormone of B-type natriuretic peptide (NT-proBNP) levels, in patients with hypertrophic cardiomyopathy (HCM p = 0.001), p = 0.03), p = 0.006), but not, however, to LAAEFr (p = 0.4). The plasma NT-proBNP levels of patients were not correlated with either (Cardiol J 2015; 22, 1: 94-100)

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“…The LAV is known to be a predictor of AF in patients with HCM [22]. In our study, both PWD and inter-atrial dyssynchrony were correlated with all phasic LAVs.…”

Section: Relationships Of Pwd and Atrial Emd To La Phasic Volumessupporting

confidence: 54%

Relationships between P wave dispersion, atrial electromechanical delay, left atrial remodeling, and NT-proBNP levels, in patients with hypertrophic cardiomyopathy

et al. 2015

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“…23,24 This is consistent with our observation that left atrial size was an independent predictor of incident AF. It has also been shown that age and congestive symptoms are independent predictors of AF occurrence.…”

Section: Discussionsupporting

confidence: 91%

Clinical Correlates and Prognostic Value of Elevated Right Atrial Pressure in Patients With Hypertrophic Cardiomyopathy

McCullough

Fifer

Mohajer

et al. 2018

Circ J

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Background:The clinical characteristics associated with elevated right atrial pressure (RAP) in hypertrophic cardiomyopathy (HCM) are unknown. Few data exist as to whether elevated RAP has prognostic implications in patients with HCM. This study investigated the clinical correlates and prognostic value of elevated RAP in HCM. Methods and Results:This retrospective cohort study was performed on 180 patients with HCM who underwent right heart catheterization between 1997 and 2014. Elevated RAP was defined as >8 mmHg. Baseline characteristics, mean pulmonary artery pressure, and mean pulmonary capillary wedge pressure (PCWP) were assessed for association with elevated RAP. The predictive value of elevated RAP for all-cause mortality and the development of atrial fibrillation (AF), ventricular tachycardia/fibrillation (VT/VF), and stroke was evaluated. Elevated RAP was associated with higher New York Heart Association class, dyspnea on exertion, orthopnea, edema, jugular venous distention, larger left atrial size, right ventricular hypertrophy, higher pulmonary artery pressure, and higher PCWP. RAP independently predicted all-cause mortality (adjusted hazard ratio [aHR] 2.18 per 5-mmHg increase, 95% confidence interval [CI] 1.05-4.50, P=0.04) and incident AF (aHR 1.85 per 5-mmHg increase, 95% CI 1.20-2.85, P=0.005). Elevated RAP did not predict VT/VF (P=0.36) or stroke (P=0.28). Conclusions:Elevated RAP in patients with HCM is associated with left-sided heart failure and is an independent predictor of all-cause mortality and new-onset AF.

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“…Although the present study did not find significant differences in LAD between nonobstructive HCM patients with PAF and those with NSR, there are reports of the detection of PAF patients with HCM using other markers such us echocardiographic measurements and 12-lead electrocardiographic findings [38][39][40]. In conclusion, the present study indicated that plasma BNP level is clinically useful for the identification of HCM patients who have a risk of PAF.…”

Section: Discussioncontrasting

confidence: 78%

Association of elevated plasma B-type natriuretic peptide levels with paroxysmal atrial fibrillation in patients with nonobstructive hypertrophic cardiomyopathy

Matsuura

Murakami

Hina

et al. 2008

Clinical Biochemistry

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Left atrial volume and the risk of paroxysmal atrial fibrillation in patients with hypertrophic cardiomyopathy

Cited by 126 publications

References 17 publications

Relationships between P wave dispersion, atrial electromechanical delay, left atrial remodeling, and NT-proBNP levels, in patients with hypertrophic cardiomyopathy

Relationships between P wave dispersion, atrial electromechanical delay, left atrial remodeling, and NT-proBNP levels, in patients with hypertrophic cardiomyopathy

Clinical Correlates and Prognostic Value of Elevated Right Atrial Pressure in Patients With Hypertrophic Cardiomyopathy

Association of elevated plasma B-type natriuretic peptide levels with paroxysmal atrial fibrillation in patients with nonobstructive hypertrophic cardiomyopathy

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