Left atrial volume and function in patients following ST elevation myocardial infarction and the association with clinical outcome: a cardiovascular magnetic resonance study

Abstract

In STEMI patients, impaired LA fractional change is independently associated with outcome and provide incremental prognostic information to established predictors including LAmax.

EHRA/HRS/APHRS/SOLAECE expert consensus on atrial cardiomyopathies: definition, characterization, and clinical implication

“…[311][312][313][314][315][316] In the absence of MVD, an increase in LA size most commonly reflects increased wall tension as a result of increased LA pressure, [317][318][319][320] as well as impairment in LA function secondary to atrial myopathy. 321,322 A clear relationship exists between an enlarged LA and the incidence of atrial fibrillation and stroke, [323][324][325][326][327][328][329][330][331][332] risk for overall mortality after myocardial infarction, 321,322,333,334 risk for death and hospitalization in patients with dilated cardiomyopathy, [335][336][337][338][339][340][341][342][343][344] and major cardiac events or death in patients with diabetes mellitus. 345 left atrium enlargement is a marker of both the severity and chronicity of diastolic dysfunction and magnitude of LA pressure elevation.…”

Left atrial volume in patients with HER2‐positive breast cancer: One step further to predict trastuzumab‐related cardiotoxicity

“…Left atrium (LA) enlargement has proven to be a powerful predictor of adverse outcomes in several disease entities. [9][10][11] However, no data are available correlating TZ-related LV dysfunction to baseline left atrial volume index (LAVI). Therefore, the aim of this single-center observational study was to investigate the relationship between baseline LAVI and cardiotoxicity development, and to test the hypothesis that baseline LA volume enlargement could predict TZrelated LV dysfunction.…”

The prognostic value of left atrial function assessed by TDI after myocardial infarction (comparison between ST and non ST segment elevation myocardial infarction)

“…the main findings of this study are: (i) LA fractional change, LA passive fraction, and LAmin reflect acute and chronic heart disease, whereas LAmax mainly reflects chronic heart disease; and (ii) LA fractional change provides independent prongostic information beyond known predictors. (23) Recently, using computed tomography, Kühl et al have demonstrated that impaired LA function is associated with a poorer prognosis in patients with non ST-segment elevation myocardial infarction (NSTEMI). However, patients with NSTEMI often have a more longstanding history of ischaemic heart disease, increased prevalence of comorbidities, smaller acute ischaemic burden, and a different prognosis from those with STEMI.…”