Left Atrial Remodeling in Segmental vs. Global Mitral Valve Prolapse　– Three-Dimensional Echocardiography –

Atrial Fibrillation and Mitral Valve Prolapse

“…(22–24) Basal myocardial left ventricular fibrosis is also common in patients with DMR. (25) We can postulate that atrial fibrosis reflects abnormal wall stresses from the prolapsing leaflets, expanding annulus and dilated atrium (Figure1, 2–4)(26–28) and impinging MR jets, possibly augmented by abnormal interstitial mechanosensing due to DMR-causing mutations. (29)…”